FB2024_03 , released June 25, 2024
Allele: Dmel\Saysd1ΔKRRK
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General Information
Symbol
Dmel\Saysd1ΔKRRK
Species
D. melanogaster
Name
FlyBase ID
FBal0388236
Feature type
allele
Associated gene
Dmel\Saysd1
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class

loss of function allele

Mutagen
Nature of the Allele
Allele class

loss of function allele

(Wang et al., 2023)
Mutagen
CRISPR/Cas9
(Wang et al., 2023)
Progenitor genotype
Cytology
Description

A 12-nt deletion in the Saysd1 locus. The resulting allele encodes a protein missing four charged residues (KRRK) in the ribosome-binding N17 domain.

(Wang et al., 2023)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
deletion
3R:25,215,086..25,215,097 [-]
Comment:

A 12bp deletion removes amino acids 15-18 (KRRK) in the Saysd1 ribosome-binding N17 domain.

(Wang et al., 2023)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Saysd1ΔKRRK
      ΔKRRK
      (Wang et al., 2023)
      Name Synonyms
      Secondary FlyBase IDs
        References (1)