FB2024_02 , released April 23, 2024
FB2024_02 , released April 23, 2024
CV Term Report
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General Information
Term dopaminergic PPL1 neuron ID (Ontology) FBbt:00100219 (Fly Anatomy)
Definition A dopaminergic neuron whose cell body is located in a cluster of approximately 12 cell bodies in the cortex of the posterior inferior lateral protocerebrum of the adult brain, immediately lateral to the mushroom body calyx. Members of this group project to various parts of the mushroom body: the tip of the alpha lobe; the tip of the alpha' lobe; the upper portion of the alpha lobe segment 2; alpha lobe segment 1 and the lower part of segment 2; and the pedunculus and spur (Mao and Davis, 2009). Long-range fibers project bilaterally to and arborize in the tips and stalks of the alpha and alpha' lobes, the heel and the peduncle (Claridge-Chang et al., 2009). Other members of this group arborize in areas other than the mushroom body: the edge of the medial portions of the medial lobes; broad areas surrounding the ipsilateral vertical lobes; areas posterior to the ipsilateral vertical lobes; the entire span of the superior arch (Mao and Davis, 2009) and the central complex (Claridge-Chang et al., 2009).[ FlyBase:FBrf0048550 FlyBase:FBrf0208427 FlyBase:FBrf0208958 FlyBase:FBrf0233706 ]
Also Known As "DL1 cell cluster neuron" ; "PPL1" ; "PPL1 cluster neuron" (for all, see Synonyms field below)
Comment Mao and Davis (2009) identify 8 protocerebral clusters coincidentally positive for TH-GAL4 activity and tyrosine hydroxylase immunoreactivity, implying these cells are dopaminergic. Mao and Davis (2009) use a heat shock-induced flip-out system to visualize the projection pattern of one or a few GFP-positive clones. The cluster of PPL1 neurons was judged by a curator to correspond to the DL1 cell cluster in Budnik and White (1988).
Links to Extrernal Ontologies
VFB:FBbt_00100219
Annotations
Records annotated with this term OR any of its CHILD TERMS
Records annotated with this exact term (annotations to child terms are NOT included)
Data Class Field Records
Alleles (FBal)  PHENOTYPE_MANIFEST_IN      98
Insertions (FBti)  EXPRESSION_STAGE_TISSUE_POSITION       9
Insertions (FBti)  PHENOTYPE_MANIFEST_IN      11
Constructs (FBtp)  PHENOTYPE_MANIFEST_IN      72
show Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
 Full annotation statements 
Relevant FlyBase reports
 Alleles  Genes Insertions Constructs
 dopaminergic PPL1 neuron (all annotations which use CV term, excluding "NOT" statements)      98      7      1     20     99
     dopaminergic PPL1 neuron | adult stage      30       --       --       3     23
     dopaminergic PPL1 neuron | adult stage | chemical conditional       2       --       --       --       2
     dopaminergic PPL1 neuron | adult stage | decreased number      18       --       --       4     11
     dopaminergic PPL1 neuron | adult stage | increased number       2       --       --       --       2
     dopaminergic PPL1 neuron | adult stage | progressive      18       --       --       2     13
     dopaminergic PPL1 neuron | decreased number       9       --       --       1      6
     dopaminergic PPL1 neuron | heat sensitive       1       --       --       --       --
     dopaminergic PPL1 neuron | increased number       2       --       --       --       2
     dopaminergic PPL1 neuron | progressive      10       --       --       --       7
     dopaminergic PPL1 neuron | progressive | heat sensitive       1       --       --       1       --
Spanning Tree (Parents/Children)
Only view relationship:
adult head
 |__adult brain______________________
adult central nervous system         |
 |__adult brain______________________|
brain                                |
 |__adult brain______________________|
dopaminergic neuron                  |
 |__adult dopaminergic neuron________|
adult neuron                         |
 |__adult CNS neuron_________________|
adult aminergic neuron               |
 |__adult dopaminergic neuron________|
CNS neuron                           |
 |__supraesophageal ganglion neuron__|
 |__adult CNS neuron_________________|
                                     dopaminergic PPL1 neuron  347 rec.
                                      |__dFB neuron of the dopaminergic PPL1 cluster 60 rec.
                                      |   |__dopaminergic PPL1 fan-shaped body layer 5 neuron 4 rec.
                                      |   |__dopaminergic PPL1 fan-shaped body layer 6 neuron 5 rec.
                                      |   |__dopaminergic PPL1 fan-shaped body layer 7 neuron 4 rec.
                                      |__DP neuron of the dopaminergic PPL1 cluster 5 rec.
                                      |__MB-AMP neuron of the dopaminergic PPL1 cluster 24 rec.
                                      |__MB-SV neuron of the dopaminergic PPL1 cluster 50 rec.
                                      |   |__bSMP-gamma neuron of the dopaminergic PPL1 cluster 27 rec.
                                      |   |__SMP neuron of the dopaminergic PPL1 cluster 36 rec.
                                      |   |__SMP-gamma neuron of the dopaminergic PPL1 cluster 32 rec.
                                      |   |__SMP-PED neuron of the dopaminergic PPL1 cluster 31 rec.
                                      |__mushroom body PPL1 neuron 121 rec.
                                          |__dopaminergic PPL1 neuron 2
                                          |__MB-alpha neuron of the dopaminergic PPL1 cluster 68 rec.
                                          |__MB-alpha' neuron of the dopaminergic PPL1 cluster 50 rec.
                                          |__mushroom body medial-vertical lobe arborizing neuron 1 74 rec.
                                          |__mushroom body pedunculus-medial lobe arborizing neuron 1 78 rec.
                                          |__mushroom body vertical lobe arborizing neuron 1 82 rec.
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Is a supraesophageal ganglion neuron
adult dopaminergic neuron
adult CNS neuron
Part of adult brain
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Synonyms
  • "DL1 cell cluster neuron" EXACT[ FlyBase:FBrf0048550 ]
    "PPL1" EXACT VFB_SYMBOL[ FlyBase:FBrf0208427 ]
    "PPL1 cluster neuron" EXACT
    "protocerebral posteriolateral dopaminergic cluster neuron 1" EXACT
    "protocerebral posterior lateral cluster neuron 1" EXACT
    "TH-positive posteriolateral cluster neuron 1" EXACT
Secondary IDs
hide External Crossreferences & Linkouts
VFB:FBbt_00100219