FB2024_03 , released June 25, 2024
FB2024_03 , released June 25, 2024
CV Term Report
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General Information
Term neuroblast NB7-2 ID (Ontology) FBbt:00001392 (Fly Anatomy)
Definition Neuroblast that delaminates at S2 in the intermediate column and generates around 12 primary interneurons (Schmid et al., 1999). In the embryo, one of these cells can be found in each hemisegment from S1-A9 (Birkholz et al., 2013; Urbach et al., 2016). In the larva, it resumes proliferation in segments S3-T3, but its secondary lineage is dramatically reduced in T3 (Lacin and Truman, 2016). The neurons that develop from this neuroblast after larval hatching form postembryonic lineage 11 (Lacin and Truman, 2016).[ FlyBase:FBrf0112030 FlyBase:FBrf0221210 FlyBase:FBrf0228122 FlyBase:FBrf0231327 FlyBase:FBrf0232096 ]
Also Known As "lineage 11 neuroblast" ; "neuroblast 11"
Comment Birkholz et al. (2015) suggest that NB7-2 does not generate a postembryonic lineage and NB6-4 generates postembryonic lineage 11, but Lacin and Truman (2016) provide lineage tracing and marker data showing that NB7-2 generates lineage 11. Lacin and Truman (2016) do not show data for neuromeres anterior to S3 (labial).
Links to Extrernal Ontologies
VFB:FBbt_00001392
Annotations
Records annotated with this term OR any of its CHILD TERMS
Records annotated with this exact term (annotations to child terms are NOT included)
Data Class Field Records
Alleles (FBal)  PHENOTYPE_MANIFEST_IN       1
Insertions (FBti)  EXPRESSION_STAGE_TISSUE_POSITION       2
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Relevant FlyBase reports
 Alleles  Genes Insertions Constructs
 neuroblast NB7-2 (all annotations which use CV term, excluding "NOT" statements)       2      1     13      2      5
Spanning Tree (Parents/Children)
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central nervous system
 |__segmentally-repeated neuroblast__
neuroblast                           |
 |__stage 2 neuroblast_______________|
 |__segmentally-repeated neuroblast__|
                                     neuroblast NB7-2  23 rec.
                                      |__abdominal neuroblast NB7-2
                                      |__labial neuroblast NB7-2
                                      |__mandibular neuroblast NB7-2
                                      |__maxillary neuroblast NB7-2
                                      |__thoracic neuroblast NB7-2
                                          |__mesothoracic neuroblast NB7-2
                                          |__metathoracic neuroblast NB7-2
                                          |__prothoracic neuroblast NB7-2
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Is a stage 2 neuroblast
segmentally-repeated neuroblast
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VFB:FBbt_00001392