FB2024_03 , released June 25, 2024
FB2024_03 , released June 25, 2024
CV Term Report
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General Information
Term distal medullary amacrine neuron Dm8 ID (Ontology) FBbt:00013774 (Fly Anatomy)
Definition Glutamatergic (Gao et al., 2008; Karuppudurai et al., 2014) distal medullary amacrine neuron that branches extensively in medulla layer M6A (Fischbach and Dittrich, 1989; Takemura et al., 2013; Nern et al., 2015), spanning approximately 16 medulla columns (Karuppudurai et al., 2014), with centrifugal projections back to layer M4 (Takemura et al., 2013; Nern et al., 2015). The highest arbor density and longest distal projection are usually found in one optic column (its 'home column'), near the center of the M6A arborization, with these columns tiling between different individual Dm8 cells, while the rest of the arbor overlaps with other Dm8 cells considerably (Gao et al., 2008; Nern et al., 2015; Kind et al., 2021). In layer M6, it is postsynaptic to several R7 photoreceptor cells and presynaptic to Tm5c (Gao et al., 2008; Takemura et al., 2013; Karuppudurai et al., 2014). The contacts with Tm5c are clustered in one column at the center of the dendritic field of Dm8 (Karuppudurai et al., 2014). It is involved in UV preference (Gao et al., 2008).[ FlyBase:FBrf0049410 FlyBase:FBrf0206213 FlyBase:FBrf0222324 FlyBase:FBrf0224070 FlyBase:FBrf0228639 FlyBase:FBrf0252485 ]
Also Known As "Dm8" ; "Dm8a"
Comment Connectivity inferred from EM reconstructions from a single EM section. The neurotransmitter was assessed in cells labelled with a glutamate GAL4 driver P\\\{GawB\}vGlut[OK371] (FBti0076967) (Gao et al., 2008), RT-PCR and by immunohistochemistry (Karuppudurai et al., 2014). Connectivity with R7 was assessed by EM reconstruction of a single medulla column (Gao et al., 2008) or reconstruction of serial-section TEM (Takemura et al., 2013).
Links to Extrernal Ontologies
VFB:FBbt_00013774
Annotations
Records annotated with this term OR any of its CHILD TERMS
Records annotated with this exact term (annotations to child terms are NOT included)
Data Class Field Records
Alleles (FBal)  PHENOTYPE_MANIFEST_IN      32
Insertions (FBti)  EXPRESSION_STAGE_TISSUE_POSITION       4
Insertions (FBti)  PHENOTYPE_MANIFEST_IN       3
Constructs (FBtp)  PHENOTYPE_MANIFEST_IN      14
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 Full annotation statements 
Relevant FlyBase reports
 Alleles  Genes Insertions Constructs
 distal medullary amacrine neuron Dm8 (all annotations which use CV term, excluding "NOT" statements)      33      6      2      7     26
     distal medullary amacrine neuron Dm8 | adult stage       1       --       --       1       --
     distal medullary amacrine neuron Dm8 | adult stage | somatic clone      23       --       --       2      8
     distal medullary amacrine neuron Dm8 | somatic clone       1       --       --       --       --
Spanning Tree (Parents/Children)
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adult optic lobe neuron
 |__distal medullary amacrine neuron________
optic lobe amacrine neuron                  |
 |__distal medullary amacrine neuron________|
adult optic lobe columnar neuron            |
 |__optic lobe wide-field columnar neuron___|
adult neuron                                |
 |__adult glutamatergic neuron______________|
secondary neuron                            |
 |__Notch OFF hemilineage secondary neuron__|
Notch OFF hemilineage neuron                |
 |__Notch OFF hemilineage secondary neuron__|
glutamatergic neuron                        |
 |__adult glutamatergic neuron______________|
                                            distal medullary amacrine neuron Dm8  74 rec.
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Is a distal medullary amacrine neuron
Notch OFF hemilineage secondary neuron
adult glutamatergic neuron
optic lobe wide-field columnar neuron
Develops from immature distal medullary amacrine neuron Dm8
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Synonyms
Secondary IDs
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FlyBrain_NDB:10088
VFB:FBbt_00013774