FB2024_03 , released June 25, 2024
FB2024_03 , released June 25, 2024
CV Term Report
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General Information
Term mushroom body pedunculus-medial lobe arborizing neuron 1 ID (Ontology) FBbt:00100243 (Fly Anatomy)
Definition A neuron whose cell body is located on the inferior neuropils, lateral to the mushroom body calyx (Tanaka et al., 2008), in the dopaminergic PPL1 cluster (Aso et al., 2014). It develops from a larval mushroom body input neuron of the CP3 (DL2) lineage (Truman et al., 2023). The cell body fiber runs anteriormedially and diverges above the ellipsoid body (Tanaka et al., 2008). Its dendrite forms four main arbors, in the superior intermediate protocerebrum, superior medial protocerebrum, dorsal crepine and ventral crepine (Otto et al., 2020). Another fiber turns ventromedially and projects to the opposite hemisphere (Tanaka et al., 2008; Li et al., 2020). A third fiber (axonal) turns ventrolaterally, runs in front of the anterior surface of the gamma lobe and then below the gamma lobe, and arborizes in the spur of the gamma lobe (slice 1) and inner core of the pedunculus (Tanaka et al., 2008; Li et al., 2020; Otto et al., 2020). The contralateral fiber innervates the same mushroom body regions (Li et al., 2020). There are 1-2 neurons of this type per hemisphere (Aso et al., 2014; Li et al., 2020; Otto et al., 2020; Truman et al., 2023). It is involved in food odor attraction (Sayin et al., 2019).[ FlyBase:FBrf0205263 FlyBase:FBrf0227179 FlyBase:FBrf0243986 FlyBase:FBrf0246510 FlyBase:FBrf0248215 FlyBase:FBrf0255928 ]
Also Known As "MB-MP1" ; "PPL1-01" ; "PPL1-gamma1pedc" (for all, see Synonyms field below)
Comment Names are assigned according to the area of the mushroom body they arborize, as detailed in Tanaka et al. (2008). The PPL1 cluster was identified by TH immunostaining and using a TH-GAL4 driver (FBtp0020119) (Liu et al., 2012). 1-2 per hemisphere in Aso et al. (2014), 1 in FAFB, 2 (each with different larval precursor cell) in Truman et al. (2023).
Links to Extrernal Ontologies
VFB:FBbt_00100243
Annotations
Records annotated with this term OR any of its CHILD TERMS
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Data Class Field Records
Insertions (FBti)  EXPRESSION_STAGE_TISSUE_POSITION      10
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Relevant FlyBase reports
 Alleles  Insertions Constructs
 mushroom body pedunculus-medial lobe arborizing neuron 1 (all annotations which use CV term, excluding "NOT" statements)       1     37     10     30
Spanning Tree (Parents/Children)
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interneuron
 |__primary interneuron____________
adult neuron                       |
 |__adult CP3 lineage neuron_______|
primary neuron                     |
 |__primary interneuron____________|
mushroom body dopaminergic neuron  |
 |__mushroom body PPL1 neuron______|
adult CP3 lineage clone            |
 |__adult CP3 lineage neuron_______|
adult interneuron                  |
 |__mushroom body PPL1 neuron______|
dopaminergic PPL1 neuron           |
 |__mushroom body PPL1 neuron______|
mushroom body extrinsic neuron     |
 |__mushroom body PPL1 neuron______|
CP3 lineage neuron                 |
 |__adult CP3 lineage neuron_______|
                                   mushroom body pedunculus-medial lobe arborizing neuron 1  78 rec.
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Is a mushroom body PPL1 neuron
adult CP3 lineage neuron
primary interneuron
Develops from larval mushroom body modulatory input neuron
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Synonyms
Secondary IDs
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FlyBrain_NDB:10468
VFB:FBbt_00100243