FB2024_04 , released June 25, 2024
FB2024_04 , released June 25, 2024
CV Term Report
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Term binary expression system - regulatory region ID (Ontology) FBcv:0005060 (FlyBase CV)
Definition Specific DNA sequence that is used as the effector in a binary expression system. This system requires a transactivator ('driver') that binds to a specific DNA sequence ('regulatory region' or 'effector'). A driver encoded by one transgenic locus or modified endogenous locus is used to drive expression of a downstream 'responder' or 'reporter' encoded by another transgenic locus or modified endogenous locus, by fusing the regulatory region sequence to which the driver binds upstream of the responder sequence. The temporal and spatial expression pattern of the responder thus depends on the regulatory elements used to drive expression of the driver. In addition, a specific repressor protein may be available which prevents the transactivator from driving expression, allowing further refinement of the expression pattern of the responder.[ FlyBase:FBrf0216478 ]
Also Known As "binary expression system - effector"
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 binary expression system - regulatory region (all annotations which use CV term, excluding "NOT" statements)      15
     carries tool | binary expression system - regulatory region       3
     has reg region | binary expression system - regulatory region      15
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 |__binary expression system component__________
engineered regulatory region                    |
 |__engineered transcription regulatory region__|
                                                binary expression system - regulatory region  15 rec.
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engineered transcription regulatory region
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