FB2024_02 , released April 23, 2024
FB2024_02 , released April 23, 2024
CV Term Report
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Term binary expression system - repressor ID (Ontology) FBcv:0005061 (FlyBase CV)
Definition Repressor that can be used to regulate expression in a binary expression system. This system requires a transactivator ('driver') that binds to a specific DNA sequence ('regulatory region' or 'effector'). A driver encoded by one transgenic locus or modified endogenous locus is used to drive expression of a downstream 'responder' or 'reporter' encoded by another transgenic locus or modified endogenous locus, by fusing the regulatory region sequence to which the driver binds upstream of the responder sequence. The temporal and spatial expression pattern of the responder thus depends on the regulatory elements used to drive expression of the driver. In addition, a specific repressor protein may be available which prevents the transactivator from driving expression, allowing further refinement of the expression pattern of the responder.[ FlyBase:FBrf0216478 ]
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 Genes Experimental Tools
 binary expression system - repressor (all annotations which use CV term, excluding "NOT" statements)       2      3
     encodes tool | binary expression system - repressor       --       3
     tagged with | binary expression system - repressor       --       1
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  experimental tool descriptor
   |__binary expression system component
       |__binary expression system - repressor  7 rec.
           |__binary expression system - conditional repressor 2 rec.
               |__binary expression system - temperature conditional repressor 2 rec.
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