Note:The pathway gene tables display genes that have been experimentally shown to act within the pathway or modify pathway activity. We welcome any feedback to help improve the usefulness and accuracy of these gene lists.

A recent paper "The Drosophila tumor necrosis factor receptor, Wengen, couples energy expenditure with gut immunity" (FBrf0256741) shows that in the context of ISC wgn can inhibit the JNK cascade. This is in contrast with the role of Tumor Necrosis Factor α signaling in promoting the JNK cascade (FBrf0162270). As this may be independent of the ligand egr, it has not been curated as part of the TNFα-Eiger Signaling Pathway.