Spd2, DSpd-2, Cep192, D-Spd2, DSpd2
recruitment of pericentriolar material to sperm centrioles after fertilization
Please see the JBrowse view of Dmel\spd-2 for information on other features
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AlphaFold produces a per-residue confidence score (pLDDT) between 0 and 100. Some regions with low pLDDT may be unstructured in isolation.
Low-frequency RNA-Seq exon junction(s) not annotated.
Gene model reviewed during 5.45
2.9, 1.9 (northern blot)
There is only one protein coding transcript and one polypeptide associated with this gene
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Dmel\spd-2 using the Feature Mapper tool.
The testis specificity index was calculated from modENCODE tissue expression data by Vedelek et al., 2018 to indicate the degree of testis enrichment compared to other tissues. Scores range from -2.52 (underrepresented) to 5.2 (very high testis bias).
JBrowse - Visual display of RNA-Seq signals
View Dmel\spd-2 in JBrowse3-44
3-39.2
Please Note FlyBase no longer curates genomic clone accessions so this list may not be complete
Please Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see JBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
spd-2 is required for efficient recruitment of pericentriolar material.
spd-2 is required for pericentriolar material recruitment and astral microtubule nucleation in both neuroblasts and spermatocytes.
spd-2 is essential for proper pericentriolar material recruitment to the sperm centriole, and hence for microtubule nucleation and pronuclear fusion.
RNAi screen using dsRNA made from templates generated with primers directed against this gene causes decreased γ-tubulin staining at the spindle pole when assayed in S2 cells. This phenotype can be observed when the screen is performed with or without Cdc27 dsRNA.
Transcription unit defined during molecular analysis of tra gene region.
"CG18217" is a putative chimeric gene derived from the "spd-2" and "CG4098" genes (where coding sequences of the two parental genes contribute to the coding sequence of the chimeric gene).
Source for identity of: spd-2 CG17286