GLI, Gli1
Foreign sequence; species == Homo sapiens; gene == GLI1; HGNC:4317.
Up-to-date information on gene product function can be found by searching UniProtKB for proteins or RNAcentral for non-coding RNAs.
Click to get a list of regulatory features (enhancers, TFBS, etc.) and gene disruptions (point mutations, indels, etc.) within or overlapping Hsap\GLI1 using the Feature Mapper tool.
The testis specificity index was calculated from modENCODE tissue expression data by Vedelek et al., 2018 to indicate the degree of testis enrichment compared to other tissues. Scores range from -2.52 (underrepresented) to 5.2 (very high testis bias).
JBrowse - Visual display of RNA-Seq signals
View Hsap\GLI1 in JBrowsePlease Note This section lists cDNAs and ESTs that fall within the genomic extent of the gene model, which may include cDNAs and ESTs of genes within introns, or of overlapping genes. Please see JBrowse for alignment of the cDNAs and ESTs to the gene model.
For each fully sequenced cDNA the DGRC maintains various forms of the cDNA (e.g tagged or untagged) in several different host vectors for subsequent cloning and expression in Drosophila and Drosophila cell lines.
ci null alleles are partially functionally complemented by Hsap\GLI, which rescues viability to late third instar, but produces larvae with grossly enlarged wing discs. ci null alleles are also partially functionally complemented by a combination of Hsap\GLI and Hsap\GLI3, rescuing to pupal or late third instar larvae and producing wild-type wing discs.
FlyBase curator comment: Symbol and name changed to reflect current HGNC symbol and name (19th Nov. 2012).