FB2024_03 , released June 25, 2024
Physical Interaction report
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General Information
Interaction Type
physical association
Interacting Genes
Atx2, tim
FlyBase ID
FBig0000098059
Interaction Network
Interactions Browser links
Atx2 network
tim network
esyN Network Diagram
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Protein
RNA
Selected Interactor(s)
Common Interactor(s)
Reported Interactions
FBrf0221582-2.coIP.PCR
Reference
Zhang et al., 2013
Description
physical association
Assay
Collection
Source/Stage
adult head / adult stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
Atx2 

ATX2

bait
tim 

tim

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was adult head of wild type fly line; bait produced from endogenous; prey produced from endogenous gene.

(Zhang et al., 2013)
FBrf0221600-15.coIP.PCR
Reference
Lim and Allada, 2013
Description
physical association
Assay
Collection
Source/Stage
adult head / adult stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
Atx2 

ATX2

bait

FLAG tag

Atx2 
tim 

tim

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Atx2 
PABP-interacting motif 2
mutation disrupting interaction
aa 855-869

\'ATX2ΔPAM2\'

Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was adult head of transgenic fly line; bait produced from tagged transgenic construct; prey produced from endogenous gene.

(Lim and Allada, 2013)

Atx2 requires an intact PABP-interacting motif to bind target transcripts.

(Lim and Allada, 2013)

Atx2 binds target transcripts in the absence of tyf protein.

(Lim and Allada, 2013)
FBrf0235227-29.coIP.PCR
Reference
Lee et al., 2017
Description
physical association
Assay
Collection
Source/Stage
head / adult stage
Cell line used
Participants
Corresponds to
Reported as
Role
Note
Atx2 

Atx2

bait
tim 

tim

prey
Experimental entities
Corresponds to
Identifier
Reported
Role
Note
Subregions with role in interaction
Corresponds to
Description
Role
Coordinates
Note
Isoform-specific participants
Corresponds to
Description
Role
Note
Comments concerning this interaction

Source was adult heads; bait produced from endogenous gene; prey produced from endogenous gene.

(Lee et al., 2017)
External Crossreferences and Linkouts ( 1 )
Linkouts
MIST - An integrated Molecular Interaction Database
References (3)