Merabet, S., Lohmann, I. (2015). Toward a new twist in Hox and TALE DNA-binding specificity.  Dev. Cell 32(3): 259--261.

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Note

Hox proteins gain specificity by interacting with TALE-class cofactors. In a recent issue of Cell and in this issue of Developmental Cell, Crocker et al. (2015) and Amin et al. (2015), respectively, demonstrate that non-canonical Hox/TALE binding sequences play a major role in the regionalized regulation of target gene expression in vivo.