FlyBase Insertion Report: Dmel\P{GawB}Hr39[c739]

General Information

Symbol

Dmel\P{GawB}Hr39^c739

Species

D. melanogaster

Name

FlyBase ID

FBti0002926

Feature type

transposable_element_insertion_site

Also Known As

c739-GAL4, c739, c739 GAL4, GAL4-c739, c739GAL4

Description

Inserted Element

P{GawB}

LINE ID

Affected gene(s)

Hr39, Scer\GAL4

Viability / fertility

viable

Associated allele(s)

Hr39^c739, Scer\GAL4^c739

Stock availability

2 publicly available

Genomic Location

Chromosomal Location

2L ( 39B4-39C1 )

Sequence Location

Target / Docking site

Member of Large Scale Dataset(s)

Dataset

Description

Detailed Mapping Data

Chromosome (arm)

Sequence Location

Orientation

Cytological location (computed by FlyBase)

39B4-39C1 (near gene of known cytology)

Cytological location (reported)

40A (in situ hybridization reported)

(Tettamanti et al., 1997, Yang et al., 1995)

Insertion into Natural transposon

Comments concerning location

Sequence Data

Flanking sequence

Inserted Element

Construct

P{GawB}

Size (Kb)

11.279

Component Allele(s)

Scer\GAL4^wB

w^+mW.hs

Molecular map

Affected Gene(s)

Insertion may affect gene

Hr39

(Boulanger et al., 2011, Bates et al., 2010)

Scer\GAL4

(Ueno et al., 2013, Chen and Ganetzky, 2012, Chen et al., 2012, Ishida et al., 2012, Keleman et al., 2012, Zanini et al., 2012, Zhou et al., 2012, Bang et al., 2011, Christiansen et al., 2011, Copf et al., 2011, Kahsai and Winther, 2011, Knapek et al., 2011, Lee et al., 2011, Stavropoulos and Young, 2011, Thum et al., 2011, Bates et al., 2010, Buchanan and Davis, 2010, Hekmat-Scafe et al., 2010, Kahsai et al., 2010, Knight et al., 2010, Pauls et al., 2010, Sinakevitch et al., 2010, Tan et al., 2010, Xiong et al., 2010, Aso et al., 2009, Blum et al., 2009, Donlea et al., 2009, Lin et al., 2009, Mao and Davis, 2009, Moressis et al., 2009, van Swinderen et al., 2009, Zhao et al., 2009, Chen et al., 2008, Keleman et al., 2007, Krashes et al., 2007, Liu et al., 2007, Tzortzopoulos and Skoulakis, 2007, Wang et al., 2007, Bhandari et al., 2006, Ferris et al., 2006, Joiner et al., 2006, Yu et al., 2006, Martini and Davis, 2005, Masuda-Nakagawa et al., 2005, Ramaekers et al., 2005, Wilson and Laurent, 2005, Isabel et al., 2004, Chang et al., 2003, McGuire et al., 2003, Nicolai et al., 2003, Zhu et al., 2003, Kido and Ito, 2002, Kurusu et al., 2002, Rodan et al., 2002, Cheng et al., 2001, McGuire et al., 2001, An et al., 2000, Zars et al., 2000, Armstrong et al., 1998, Kraft et al., 1998, Moreau-Fauvarque et al., 1998, Manseau et al., 1997, Tettamanti et al., 1997, Casares et al., 1996, O'Dell et al., 1995, Yang et al., 1995)

Variant Molecular Consequences

Phenotypic Data

Associated Allele

Phenotypic Data

Hr39^c739

Phenotypic Class Phenotype Manifest in Detailed Description

Scer\GAL4^c739

Phenotypic Class Phenotype Manifest in Detailed Description

Expression Data

Reporter Expression

No Assay Recorded

Stage

Tissue/Position (including subcellular localization)

Reference

adult stage

Kenyon cell

(Parker et al., 1995)

adult mushroom body | restricted

(Yeh et al., 1995)

distribution deduced from reporter (Gal4 UAS)

Stage

Tissue/Position (including subcellular localization)

Reference

(Kim et al., 2007)

(Tettamanti et al., 1997)

Kenyon cell | subset

(Tettamanti et al., 1997)

mushroom body pedunculus | restricted

(Tettamanti et al., 1997)

larval stage -- adult stage

adult mushroom body alpha-lobe

(Nicolai et al., 2003)

first instar larval stage -- second instar larval stage

Kenyon cell

(Kurusu et al., 2002)

mushroom body pedunculus

(Kurusu et al., 2002)

lobe system of mushroom body

(Kurusu et al., 2002)

second instar larval stage -- third instar larval stage

adult mushroom body beta-lobe | restricted

(Tettamanti et al., 1997)

adult mushroom body gamma-lobe | restricted

(Tettamanti et al., 1997)

adult mushroom body alpha'-lobe | restricted

(Tettamanti et al., 1997)

adult mushroom body alpha-lobe | restricted

(Tettamanti et al., 1997)

wandering third instar larval stage

embryonic protocerebrum

(Manseau et al., 1997)

larval ventral nerve cord | restricted

(Manseau et al., 1997)

third instar larval stage L2

wing disc | restricted

(Manseau et al., 1997)

haltere disc | restricted

(Manseau et al., 1997)

pupal stage P5 -- P6 & restricted

adult mushroom body alpha-lobe

(Armstrong et al., 1998)

adult mushroom body beta-lobe

(Armstrong et al., 1998)

pupal stage P6

adult mushroom body gamma-lobe

(Armstrong et al., 1998)

pupal stage P7

adult mushroom body alpha-lobe

(Armstrong et al., 1998)

adult mushroom body beta-lobe

(Armstrong et al., 1998)

pupal stage P7 | restricted

adult mushroom body gamma-lobe

(Armstrong et al., 1998)

adult stage

GABAergic local interneuron of the adult antennal lobe

(Wilson and Laurent, 2005)

adult mushroom body beta-lobe

(Tan et al., 2010, Mao and Davis, 2009, Krashes et al., 2007, Nicolai et al., 2003, Armstrong et al., 1998)

adult mushroom body alpha-lobe

(Tan et al., 2010, Krashes et al., 2007, Armstrong et al., 1998)

ellipsoid body | faint

(Aso et al., 2009, Armstrong et al., 1998)

adult optic lobe | restricted

(Armstrong et al., 1998)

gnathal ganglion | restricted

(Armstrong et al., 1998)

superior medial protocerebrum

(Kahsai et al., 2010)

fan-shaped body

(Kahsai et al., 2010)

ellipsoid body

Comment: faint expression

(Chen et al., 2012, Kahsai et al., 2010)

alpha/beta Kenyon cell

(Shyu et al., 2017, Christiansen et al., 2011, Lee et al., 2011, Buchanan and Davis, 2010, Pauls et al., 2010, Zhu et al., 2003)

adult brain | restricted

(Shyu et al., 2017, Kahsai and Winther, 2011, Lee et al., 2011)

neuron | subset of adult brain

(Chen et al., 2012)

adult mushroom body

Comment: strong expression

(Chen et al., 2012)

neuron of the dorsal anterior lateral group of the protocerebrum

Comment: faint expression

(Chen et al., 2012)

eye

Comment: faint expression

(Chen et al., 2012)

adult mushroom body | restricted

(Tettamanti et al., 1997)

adult antennal lobe local neuron | faint

(Armstrong et al., 1998)

fan-shaped body | dorsal

(Kahsai and Winther, 2011)

adult protocerebral SMP Tachykinin neuron | restricted

(Kahsai and Winther, 2011)

mushroom body beta lobe surface layer | intense

(Aso et al., 2009)

mushroom body alpha lobe surface layer | intense

(Aso et al., 2009)

mushroom body beta lobe posterior layer

(Aso et al., 2009)

mushroom body alpha lobe posterior layer

(Aso et al., 2009)

mushroom body beta lobe core layer | intense

(Aso et al., 2009)

mushroom body alpha lobe core layer | intense

(Aso et al., 2009)

adult antennal lobe

(Aso et al., 2009)

medulla

(Aso et al., 2009)

adult protocerebrum | restricted

(Aso et al., 2009)

inferior neuropils

(Aso et al., 2009)

adult antennal nerve

(Aso et al., 2009)

adult deutocerebrum | faint

(Aso et al., 2009)

adult gnathal ganglion

(Aso et al., 2009)

alpha/beta Kenyon cell | subset

(Perisse et al., 2013)

adult mushroom body alpha-lobe

(Pauls et al., 2010)

adult mushroom body beta-lobe

(Pauls et al., 2010)

adult stage | male

adult mushroom body alpha-lobe

(Blum et al., 2009)

adult mushroom body beta-lobe

(Blum et al., 2009)

Additional Information

Statement

Reference

Drives expression primarily in mushroom body structures at larval, pupal, and adult stages. Drives expression in only a few alpha'/beta' neurons.

(FlyBase Curators, 2017)

ScerGAL4^NP0385 drives expression in neurons with cell bodies located lateral to the antennal lobes (AL). Some of the labeled neurons innervate the AL.

(Thum et al., 2011)

ScerGAL4^c739 labels the mushroom body alpha/beta neurons. Co-expression with presynaptic and postsynaptic markers labels distinct domains of Kenyon cell terminals in the calyx of the mushroom body.

(Christiansen et al., 2011)

ScerGAL4^c739 is expressed in a subset of cells in the adult brain, including the mushroom body alpha/beta neurons.

(Lee et al., 2011)

ScerGAL4^c739 drives expression in approximately 16 columnar neurons in the superior medial protocerebrum that innervate the fan shaped body.

(Kahsai et al., 2010)

Expression is limited to alpha and beta neurons in the adult mushroom body.

(Blum et al., 2009)

Expression of ScerGAL4^c739 is not evident in the alpha'-lobes, the beta'-lobes, or the gamma-lobes.

(Krashes et al., 2007)

In early larval stages ScerGAL4^c739 is widely expressed in most of the Kenyon cells, and is seen throughout most axons of the pedunculus and mushroom body lobes in a pattern similar to Fas2. By third instar, expression becomes restricted to a small group of cells near each neuroblast whose projections pass through the inner layer of the pedunculus and lobes.

(Kurusu et al., 2002)

Expression of ScerGAL4^c739 in the alpha- and beta-lobes of the mushroom body is restricted in early and mid-pupal stages, but becomes extensive from late-pupal stage onwards. Gamma-lobe expression is extensive in mid-pupal stage, but is reduced by late-pupal stage and lost in adults.

(Armstrong et al., 1998)

In third instar larva, expression in central brain; in 2 longitudinal stripes in the ventral ganglion; in the pouch region of the wing and haltere discs; little or no expression in other discs.

(Manseau et al., 1997)

Larval expression is observed in subset of Kenyon cells in each of four clusters, in the calyx, and the in the circumference of the pedunculus. In the second and third larval instars, expression is also observed in the cores of the α, α', β and γ lobes of the mushroom body.

(Tettamanti et al., 1997)

Marker for

adult mushroom body beta-lobe

(Mao and Davis, 2009)

alpha/beta Kenyon cell

(Christiansen et al., 2011, Lee et al., 2011)

Reflects expression of

Reporter construct used in assay

Avic\GFP^UAS.cYa

(Kurusu et al., 2002)

Avic\GFP^S65T.UAS

(Nicolai et al., 2003)

ttk^UY181

(Nicolai et al., 2003)

RN-tre^UY333

(Nicolai et al., 2003)

Mtch^UY627

(Nicolai et al., 2003)

UY2635^UY2635

(Nicolai et al., 2003)

ttk^p69.UAS

(Nicolai et al., 2003)

ttk^p88.UAS

(Nicolai et al., 2003)

Nf1^UAS.cBa

(Buchanan and Davis, 2010)

gish^S.UAS

(Tan et al., 2010)

gish^L.UAS

(Tan et al., 2010)

Mmus\Cd8a^UAS.cLa.EGFP

(Kahsai and Winther, 2011, Lee et al., 2011, Kahsai et al., 2010, Pauls et al., 2010, Aso et al., 2009, Blum et al., 2009, Mao and Davis, 2009, Krashes et al., 2007)

shi^1.UAS

(Kahsai et al., 2010, Krashes et al., 2007)

Ecol\lacZ^UAS.cBa

(Armstrong et al., 1998)

Tk^RNAi.UAS.cWa

(Kahsai et al., 2010)

Scer\GAL80^Mef2.mb247

(Krashes et al., 2007)

Avic\GFP^{Cameleon2.1.UAS}

(Thum et al., 2011)

Btau\MAPT^UAS.cKa

(Kim et al., 2007)

Disc\RFP^{mCh.UAS.Tag:TS(brpS)}

(Christiansen et al., 2011)

Data on Genetic Line

Line ID

Origin as a multiple insertion line

Progenitor(s) within the Genome

Related Aberration or Balancer

Aberration

Balancer

Stocks (2)

Bloomington

7362

y¹ w^67c23; P{GawB}Hr39^c739

64305

y¹ w^67c23; P{GawB}Hr39^c739 P{UAS-mCD8::GFP.L}LL5

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (19)

Reported As

Symbol Synonym

739^Gal4

(Knight et al., 2010)

C739

(Gao et al., 2019, Bai et al., 2018, Miyashita et al., 2018, Thum et al., 2011, Shuai et al., 2010, Blum et al., 2009, Donlea et al., 2009, Chen et al., 2008, Wang et al., 2007, Bhandari et al., 2006)

C739-GAL4

(Wilhelm et al., 2022, Shyu et al., 2019, Shyu et al., 2017, Yang et al., 2016, Shaw et al., 2015, Wu et al., 2013, Xiong et al., 2010)

C739-Gal4

(Wu et al., 2023, Mo et al., 2022, Yang et al., 2021, Zhao et al., 2021, Xie et al., 2013, Chen and Ganetzky, 2012)

C739GAL4

(Hamid et al., 2021)

GAL4-c739

(Lin et al., 2009, Zhu et al., 2003)

P[GAL4]c739

(Cheng et al., 2001)

P{GAL4:c739}

(An et al., 2000)

P{GawB}Hr39^c739

(Zanini et al., 2012)

P{GawB}c739

(Tettamanti et al., 1997, FlyBase, 1992-)

Salivary Gland Gal4

(Salamanca et al., 2011)

c379

(Hekmat-Scafe et al., 2010)

c739

(Abubaker et al., 2024, Chen et al., 2023, Nöbel et al., 2023, Lin et al., 2022, Jia et al., 2021, Machado Almeida et al., 2021, Serway et al., 2020, Turrel et al., 2020, Deng et al., 2019, Gokhale et al., 2019, Song et al., 2019, Louis et al., 2018, Scheunemann et al., 2018, Turrel et al., 2018, Turrel et al., 2017, Turrel et al., 2016, Bai and Sehgal, 2015, Bourdet et al., 2015, Boto et al., 2014, Lin et al., 2014, Ishimoto et al., 2013, Ueno et al., 2013, Weislogel et al., 2013, Huang et al., 2012, Keleman et al., 2012, Bang et al., 2011, Boulanger et al., 2011, Copf et al., 2011, Kahsai and Winther, 2011, Knapek et al., 2011, Lee et al., 2011, Hekmat-Scafe et al., 2010, Pauls et al., 2010, Pauls et al., 2010, Sinakevitch et al., 2010, Tan et al., 2010, Aso et al., 2009, Moressis et al., 2009, van Swinderen et al., 2009, Zhao et al., 2009, Chen et al., 2008, Hong et al., 2008, Krashes et al., 2007, Liu et al., 2007, Joiner et al., 2006, Martini and Davis, 2005, Masuda-Nakagawa et al., 2005, Isabel et al., 2004, McGuire et al., 2004, Kido and Ito, 2002, Kurusu et al., 2002, Rodan et al., 2002, McGuire et al., 2001, Zars et al., 2000, Armstrong et al., 1998, Moreau-Fauvarque et al., 1998, Manseau et al., 1997)

c739 GAL4

(Bouzaiane et al., 2015, Perisse et al., 2013, Plaçais et al., 2013, Fushima and Tsujimura, 2007)

c739-GAL4

(Schwartz et al., 2023, Shen et al., 2023, Hermanns et al., 2022, Sabandal et al., 2022, Kim et al., 2021, Marquilly et al., 2021, Amin et al., 2020, Sabandal et al., 2020, Wu et al., 2020, Brown et al., 2019, Al-Anzi and Zinn, 2018, Liou et al., 2018, Aranda et al., 2017, Liu et al., 2017, Ries et al., 2017, Crocker et al., 2016, Drago and Davis, 2016, Tong et al., 2016, Ichinose et al., 2015, Reynaud et al., 2015, Zhang et al., 2015, Lin et al., 2014, Fitzsimons et al., 2013, Perrat et al., 2013, Ishida et al., 2012, Christiansen et al., 2011, Fitzsimons and Scott, 2011, Kahsai and Winther, 2011, Bates et al., 2010, Kahsai et al., 2010, Leiss et al., 2009, Mao and Davis, 2009, Pagani et al., 2009, Pavlopoulos et al., 2008, Keleman et al., 2007, Mery et al., 2007, Tzortzopoulos and Skoulakis, 2007, Ramaekers et al., 2005, Chang et al., 2003)

c739-gal4

(Sabandal et al., 2021, Cervantes-Sandoval et al., 2016, Tonoki and Davis, 2015, Buchanan and Davis, 2010)

c739GAL4

(Roussou et al., 2019)

c739{GAL4}

(Krashes et al., 2007)

Name Synonyms

Secondary FlyBase IDs

References (176)

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