Mutated Mmus\Prkaca coding sequence (amino acid substitutions: H87Q and W196R) separated from Act5C promoter by an FRT cassette that contains y+t7.7 and Rnor\Cd2 sequences.
report comment: The Mmus\Pkaca (mouse PKA allele) carried in this construct is constitutively active (reduced binding to regulatory subunit). Allele Mmus\PkacaAct5C.PJ is the FRT-deleted (active) form, carried on descendant transposon P{Act5C-PKA.A902}.
report comment: The Mmus\Pkaca (mouse PKA allele) carried in this construct is constitutively active (reduced binding to regulatory subunit). Allele Mmus\PkacaAct5C.PJ is the FRT-deleted (active) form, carried on descendant transposon P{Act5C-PKA.A902}.