FB2024_03 , released June 25, 2024
Recombinant Construct: P{GMR76E11-GAL4}
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General Information
Symbol
P{GMR76E11-GAL4}
FlyBase ID
FBtp0062790
Feature type
transgenic_transposable_element
Component Allele(s)
Scer\GAL4GMR76E11
Also Known As
76E11-Gal4
Size
Expression Data
GAL4 reporter/driver
Associated insertion(s)
1 available
Molecular map
Description and Uses
Construct components
Component
Use(s)
Marker(s)
w+mC
Component allele Scer\GAL4GMR76E11
Transgenic product class
Component
Use(s)
Regulatory region(s)
GMR76E11
Encoded product / tool
GAL4
Description

A 3112 base pair fragment from the flanking non-coding or intronic region of tup is fused upstream of a Drosophila core synthetic promoter (DSCP) that is followed by sequence encoding a GAL4 driver.

(Pfeiffer et al., 2011.2.9)
Sequence Data
Sequence (FB)
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA Sequence
Extent
Segments and Size
Total Size
Left end
Right end
 
Segments
Num
Orientation
Symbol
Reference
Phenotypic Data
Expression Data
Reporter Expression
distribution deduced from reporter (Gal4 UAS)
Stage
Tissue/Position (including subcellular localization)
Reference
embryonic stage 16
embryonic/larval pericardial cell
(Morin-Poulard et al., 2022)
embryonic/larval cardial cell
(Morin-Poulard et al., 2022)
primary lobe of embryonic/larval lymph gland
(Morin-Poulard et al., 2022)
larval stage
embryonic/larval brain
(Meyer et al., 2023)
larval stage & adult stage
ventral nerve cord
(Meyer et al., 2023)
third instar larval stage
embryonic/larval pericardial cell
(Meyer et al., 2023)
embryonic/larval cardial cell
(Meyer et al., 2023)
intracardial valve cell
(Meyer et al., 2023)
embryonic/larval lymph gland
(Meyer et al., 2023)
adult stage
anterior optic tubercle | restricted
(Jenett and Svirskas, 2012.9.24)
gall | faint | restricted
(Jenett and Svirskas, 2012.9.24)
adult intracardial valve cell
(Meyer et al., 2023)
adult alary muscle cell
(Meyer et al., 2023)
adult cardial cell
(Meyer et al., 2023)
adult brain
(Meyer et al., 2023)
adult somatic muscle
(Meyer et al., 2023)
Additional Information
Statement
Reference

Activity is observed in all cardial cells of the embryo and early larvae. Expression diminishes in second instar larvae, becomes restricted to a single pair of valve cells in third instar larvae, and to the three pairs of valve cells in adults, where it is maintained throughout the lifetime. It is also active in adult alary muscles. Activty is also observed in anterior cardiomyocytes immediately anterior to the valve cells. It is also observed in unidentified cells in the brain and ventral nerve cord.

(Meyer et al., 2023)
 
Marker for
embryonic/larval cardial cell
(Morin-Poulard et al., 2022)
embryonic/larval pericardial cell
(Morin-Poulard et al., 2022)
Reflects expression of
tup
(Meyer et al., 2023, Morin-Poulard et al., 2022)
Reporter construct used in assay
Images
Virtual Fly Brain - A database to explore neuroanatomy, connectivity and gene expression
Progenitors and Descendants
progenitor(s)
pBPGUw
(Pfeiffer et al., 2011.2.9)
descendant(s)
Comments
Stocks (1)
Stocks containing insertion(s) of this recombinant construct
Bloomington
39933
w1118; P{GMR76E11-GAL4}attP2
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (4)
Reported As
Symbol Synonym
76E11-Gal4
(Meyer et al., 2023, Meyer et al., 2023, Tian et al., 2023)
GAL4-R76E11
(Turner-Evans et al., 2017)
P{GMR76E11-GAL4}
(FlyBase, 1996-)
R76E11
(Robie et al., 2017, FlyBase, 1996-)
Secondary FlyBase IDs
    References (8)