FB2024_03 , released June 25, 2024
Recombinant Construct: M{gATP7-EGFP.ALZ}
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General Information
Symbol
M{gATP7-EGFP.ALZ}
FlyBase ID
FBtp0117363
Feature type
transgenic_transposable_element
Component Allele(s)
ATP7ALZ.EGFP
Size
Expression Data
Associated insertion(s)
0 available
Molecular map
Description and Uses
Construct components
Component allele ATP7ALZ.EGFP
Transgenic product class
missense_variant
(Mercer et al., 2017)
Component
Use(s)
Regulatory region(s)
ATP7
Encoded product / tool
ATP7
Tagged with
EGFP
Description

A genomic fragment (Pacman clone CH3222-77E05) containing the entire ATP7 gene, which has been mutated to contain the amino acid replacement K552R. This mutation is equivalent to the disease-associated K832R mutation in the orthologous human ATP7A gene (associated with susceptibility to Alzheimer's disease). A EGFP tag has been inserted at the C-terminal end of the ATP7 open reading frame.

(Mercer et al., 2017)
Sequence Data
Sequence (FB)
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA Sequence
Extent
Segments and Size
Total Size
Left end
Right end
 
Segments
Num
Orientation
Symbol
Reference
Phenotypic Data
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Progenitors and Descendants
progenitor(s)
descendant(s)
Comments
Stocks (0)
Stocks containing insertion(s) of this recombinant construct
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (2)
Reported As
Symbol Synonym
M{gATP7-EGFP.ALZ}
(FlyBase, 1992-)
gATP7ALZ-GFP
(Mercer et al., 2017)
Secondary FlyBase IDs
    References (2)