FB2024_03 , released June 25, 2024
Recombinant Construct: P{Act88F.M306L}
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General Information
Symbol
P{Act88F.M306L}
FlyBase ID
FBtp0144065
Feature type
transgenic_transposable_element
Component Allele(s)
Act88FM306L
Size
Expression Data
Associated insertion(s)
0 available
Molecular map
Description and Uses
Construct components
Component allele Act88FM306L
Transgenic product class
missense_variant
(Viswanathan et al., 2020)
Component
Use(s)
Regulatory region(s)
Act88F
Encoded product / tool
Act88F
Description

Genomic fragment containing Act88F carrying an amino acid substitution equivalent to a M307L change in the orthologous human ACTC1 gene, a variant associated with hypertrophic cardiomyopathy. (FlyBase curator comment: the mutation in the human ACTC1 gene is given as M305L in FBrf0246480, M307L is the change relative to the UniProtKB:P68032 sequence. In addition, the mutation in the Act88F gene is given as M304L in FBrf0246480, however analysis of the release 6.35 annotated gene model indicates the change to be M306L).

(Viswanathan et al., 2020)
Sequence Data
Sequence (FB)
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA Sequence
Extent
Segments and Size
Total Size
Left end
Right end
 
Segments
Num
Orientation
Symbol
Reference
Phenotypic Data
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Progenitors and Descendants
progenitor(s)
descendant(s)
Comments
Stocks (0)
Stocks containing insertion(s) of this recombinant construct
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (1)
Reported As
Symbol Synonym
P{Act88F.M306L}
(FlyBase, 1992-)
Secondary FlyBase IDs
    References (2)