FB2024_02 , released April 23, 2024
FB2024_02 , released April 23, 2024
CV Term Report
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General Information
Term synapse ID (Ontology) GO:0045202 (Gene Ontology)
Definition The junction between an axon of one neuron and a dendrite of another neuron, a muscle fiber or a glial cell. As the axon approaches the synapse it enlarges into a specialized structure, the presynaptic terminal bouton, which contains mitochondria and synaptic vesicles. At the tip of the terminal bouton is the presynaptic membrane; facing it, and separated from it by a minute cleft (the synaptic cleft) is a specialized area of membrane on the receiving cell, known as the postsynaptic membrane. In response to the arrival of nerve impulses, the presynaptic terminal bouton secretes molecules of neurotransmitters into the synaptic cleft. These diffuse across the cleft and transmit the signal to the postsynaptic membrane.[ ISBN:0198506732 PubMed:24619342 PubMed:29383328 PubMed:31998110 ]
Also Known As "synaptic junction"
Comment
Links to Extrernal Ontologies
  QuickGO data     AmiGO data
Annotations
Records annotated with this term OR any of its CHILD TERMS
Records annotated with this exact term (annotations to child terms are NOT included)
Data Class Field Records
Alleles (FBal)  PHENOTYPE_MANIFEST_IN     272
Genes (FBgn)  GO_CELLULAR_COMPONENT     103
Constructs (FBtp)  PHENOTYPE_MANIFEST_IN     109
show Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
 Full annotation statements 
Relevant FlyBase reports
 Alleles Genes Constructs
 synapse (all annotations which use CV term, excluding "NOT" statements)     272    109    109
     is_active_in | synapse       --      54       --
     located_in | synapse       --      53       --
     synapse | adult stage | decreased number       7       --       5
     synapse | adult stage | increased number       6       --       5
     synapse | adult stage | increased number | somatic clone - tissue specific       2       --       --
     synapse | decreased number | larval stage       1       --       --
     synapse | embryonic stage       4       --       2
     synapse | heat sensitive       3       --       --
     synapse | increased number       4       --       4
     synapse | increased number | wandering third instar larval stage       1       --       --
     synapse | larval stage      23       --       7
     synapse | P-stage | increased number       2       --       --
     synapse | progressive | somatic clone       1       --       --
     synapse | RU486 conditional       3       --       3
     synapse | somatic clone       1       --       --
     synapse | temperature conditional       1       --       --
     synapse | wandering third instar larval stage       2       --       --
     synapse | wandering third instar larval stage | conditional       2       --       --
Spanning Tree (Parents/Children)
Only view relationship:
  cellular anatomical entity
   |__cell junction
       |__synapse  1253 rec.
           |__cerebellar Golgi cell to granule cell synapse
           |__cholinergic synapse 1 rec.
           |   |__neuromuscular junction of skeletal muscle fiber
           |__dopaminergic synapse 1 rec.
           |__excitatory synapse 1 rec.
           |   |__asymmetric, glutamatergic, excitatory synapse(+)
           |   |__excitatory neuromuscular junction(+)
           |   |__parallel fiber to Purkinje cell synapse
           |__GABA-ergic synapse
           |   |__symmetric, GABA-ergic, inhibitory synapse
           |__glutamatergic synapse 6 rec.
           |   |__asymmetric, glutamatergic, excitatory synapse(+)
           |__glycinergic synapse
           |__inhibitory synapse
           |   |__inhibitory neuromuscular junction(+)
           |   |__symmetric, GABA-ergic, inhibitory synapse
           |__neuromuscular junction 517 rec.
           |   |__excitatory neuromuscular junction(+)
           |   |__inhibitory neuromuscular junction(+)
           |   |__neuromuscular junction of myotube(+)
           |   |__neuromuscular junction of somatic muscle(+) 3 rec.
           |   |__postsynapse of neuromuscular junction(+) 20 rec.
           |__neuron to neuron synapse 42 rec.
           |   |__asymmetric synapse(+) 42 rec.
           |   |__hippocampal mossy fiber to CA3 synapse
           |   |__symmetric synapse(+)
           |__noradrenergic synapse
           |__perforant pathway to dendrate granule cell synapse
           |__polyadic synapse
           |__postsynapse 157 rec.
           |   |__dendritic spine(+) 5 rec.
           |   |__postsynapse of neuromuscular junction(+) 20 rec.
           |   |__postsynaptic cytoskeleton(+)
           |   |__postsynaptic cytosol 4 rec.
           |   |__postsynaptic endocytic zone(+) 1 rec.
           |   |__postsynaptic endosome(+) 1 rec.
           |   |__postsynaptic Golgi apparatus 4 rec.
           |   |__postsynaptic membrane(+) 110 rec.
           |   |__postsynaptic specialization(+) 51 rec.
           |   |__synaptic vesicle, recycling pool
           |__presynapse 535 rec.
           |   |__axon terminus(+) 278 rec.
           |   |__presynaptic active zone(+) 96 rec.
           |   |__presynaptic cytoskeleton(+) 14 rec.
           |   |__presynaptic cytosol 4 rec.
           |   |__presynaptic endocytic zone(+) 3 rec.
           |   |__presynaptic endosome(+) 3 rec.
           |   |__presynaptic membrane(+) 42 rec.
           |   |__synaptic vesicle(+) 213 rec.
           |   |__terminal bouton(+) 239 rec.
           |__ribbon synapse
           |   |__arciform density
           |   |__cochlear hair cell ribbon synapse
           |   |__photoreceptor ribbon synapse
           |__Schaffer collateral - CA1 synapse
           |__serotonergic synapse
           |__synaptic membrane 146 rec.
               |__dendritic spine membrane(+)
               |__extrinsic component of synaptic membrane(+) 2 rec.
               |__postsynaptic endocytic zone membrane(+)
               |__postsynaptic membrane(+) 110 rec.
               |__postsynaptic specialization membrane(+) 22 rec.
               |__presynaptic active zone membrane(+) 5 rec.
               |__presynaptic endocytic zone membrane(+) 2 rec.
               |__presynaptic membrane(+) 42 rec.
               |__presynaptic periactive zone 5 rec.
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Is a cell junction
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Synonyms
  • "electrotonic synapse" RELATED
    "mixed synapse" NARROW
    "synaptic junction" EXACT
Secondary IDs
hide External Crossreferences & Linkouts
NIF_Subcellular:sao914572699
Wikipedia:Chemical_synapse