General Information | |||
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Term | long-chain fatty acid-CoA ligase activity | ID (Ontology) | GO:0004467 (Gene Ontology) |
Definition | Catalysis of the reaction: a long-chain fatty acid + ATP + CoA = a long-chain fatty acyl-CoA + AMP + diphosphate. A long-chain fatty acid has an aliphatic tail containing 13 to 22 carbons. | ||
Also Known As | "long-chain acyl-CoA synthetase activity" ; "long-chain-fatty-acid-CoA ligase activity" ; "long-chain-fatty-acyl-CoA synthetase activity" | ||
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QuickGO data AmiGO data | |||
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Records annotated with this term OR any of its CHILD TERMS | |||
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ligase activity, forming carbon-sulfur bonds |__CoA-ligase activity_________ acid-thiol ligase activity | |__fatty acid ligase activity__| ATP-dependent activity | |__fatty acid ligase activity__| long-chain fatty acid-CoA ligase activity 21 rec. |__arachidonate-CoA ligase activity |__myristoyl-CoA ligase activity |__oleoyl-CoA ligase activity |__palmitoyl-CoA ligase activity 1 rec. |
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Is a |
fatty acid ligase activity CoA-ligase activity |
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EC:6.2.1.3 MetaCyc:PWY-5143 MetaCyc:RXN-7904 Reactome:R-HSA-159425 "Cytosolic cholate and chenodeoxycholate are conjugated with Coenzyme A (SLC27A5 BACS)" Reactome:R-HSA-192137 "THCA is conjugated with Coenzyme A (SLC27A5 BACS)" Reactome:R-HSA-193401 "THCA is conjugated with Coenzyme A (SLC27A2 VLCS)" Reactome:R-HSA-193407 "DHCA is conjugated with Coenzyme A (SLC27A5 BACS)" Reactome:R-HSA-193424 "DHCA is conjugated with Coenzyme A (SLC27A2 VLCS)" Reactome:R-HSA-193711 "3,7,24THCA is conjugated with Coenzyme A (SLC27A5 BACS)" Reactome:R-HSA-193727 "TetraHCA is conjugated with Coenzyme A (SLC27A2 VLCS)" Reactome:R-HSA-193743 "3,7,24THCA is conjugated with Coenzyme A (SLC27A2 VLCS)" Reactome:R-HSA-193766 "TetraHCA is conjugated with Coenzyme A (SLC27A5 BACS)" Reactome:R-HSA-201035 "ACSL1,3,5,6 ligate CoA to PALM to form PALM-CoA" Reactome:R-HSA-2046085 "Activation of alpha-linolenic acid to alpha-linolenoyl-CoA" Reactome:R-HSA-2046098 "Activation of linoleic acid to linoleoyl-CoA" Reactome:R-HSA-548843 "ACSL3,4 ligate CoA to AA to form AA-CoA" Reactome:R-HSA-5696004 "ACSF2 ligates CoA-SH to MCFA" Reactome:R-HSA-9734535 "SLC27A2 ligates CoA to bempedoic acid to form ETC-1002-CoA" RHEA:15421 UM-BBD_enzymeID:e0025 |