FB2024_03 , released June 25, 2024
FB2024_03 , released June 25, 2024
CV Term Report
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General Information
Term translational initiation ID (Ontology) GO:0006413 (Gene Ontology)
Definition The process preceding formation of the peptide bond between the first two amino acids of a protein. This includes the formation of a complex of the ribosome, mRNA or circRNA, and an initiation complex that contains the first aminoacyl-tRNA.
Also Known As "translation initiation"
Comment
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Annotations
Records annotated with this term OR any of its CHILD TERMS
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Data Class Field Records
Genes (FBgn)  GO_BIOLOGICAL_PROCESS      48
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 Full annotation statements 
Relevant FlyBase reports
 Genes
 translational initiation (all annotations which use CV term, excluding "NOT" statements)      48
     involved_in | translational initiation      48
Spanning Tree (Parents/Children)
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metabolic process
 |__cellular metabolic process________________
macromolecule biosynthetic process            |
 |__translation_______________________________|
cellular process                              |
 |__cellular metabolic process________________|
gene expression                               |
 |__translation_______________________________|
protein metabolic process                     |
 |__translation_______________________________|
organonitrogen compound biosynthetic process  |
 |__translation_______________________________|
                                              translational initiation  78 rec.
                                               |__cytoplasmic translational initiation 19 rec.
                                               |   |__cap-dependent translational initiation(+)
                                               |   |__cap-independent translational initiation(+) 1 rec.
                                               |   |__formation of cytoplasmic translation initiation complex 2 rec.
                                               |   |__formation of translation preinitiation complex(+) 6 rec.
                                               |   |__regulation of cytoplasmic translational initiation(+) 2 rec.
                                               |   |__translation reinitiation 6 rec.
                                               |__formation of translation initiation ternary complex 1 rec.
                                               |   |__regulation of formation of translation initiation ternary complex(+) 1 rec.
                                               |__mitochondrial translational initiation 3 rec.
                                               |   |__regulation of mitochondrial translational initiation(+)
                                               |__regulation of translational initiation 25 rec.
                                                   |__negative regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation
                                                   |__negative regulation of translational initiation(+) 10 rec.
                                                   |__positive regulation of translational initiation(+) 4 rec.
                                                   |__regulation of cytoplasmic translational initiation(+) 2 rec.
                                                   |__regulation of eIF2 alpha phosphorylation by dsRNA
                                                   |__regulation of eIF2 alpha phosphorylation by heme
                                                   |__regulation of endoplasmic reticulum stress-induced eIF2 alpha dephosphorylation(+)
                                                   |__regulation of endoplasmic reticulum stress-induced eIF2 alpha phosphorylation
                                                   |__regulation of mitochondrial translational initiation(+)
                                                   |__regulation of translational initiation by iron(+)
                                                   |__regulation of translational initiation by tRNA modification
                                                   |__regulation of translational initiation in response to stress(+) 1 rec.
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Is a cellular metabolic process
Part of translation
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Synonyms
  • "biopolymerisation" BROAD
    "biopolymerization" BROAD
    "protein synthesis initiation" BROAD
    "translation initiation" EXACT
Secondary IDs
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