FB2024_03 , released June 25, 2024
FB2024_03 , released June 25, 2024
CV Term Report
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General Information
Term protein catabolic process ID (Ontology) GO:0030163 (Gene Ontology)
Definition The chemical reactions and pathways resulting in the breakdown of a protein by the destruction of the native, active configuration, with or without the hydrolysis of peptide bonds.
Also Known As "cellular protein breakdown" ; "cellular protein catabolic process" ; "cellular protein catabolism" (for all, see Synonyms field below)
Comment
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Annotations
Records annotated with this term OR any of its CHILD TERMS
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Data Class Field Records
Genes (FBgn)  GO_BIOLOGICAL_PROCESS      10
show Full annotation statements including this term (annotations to child terms are NOT included), and relevant FlyBase records
 Full annotation statements 
Relevant FlyBase reports
 Genes
 protein catabolic process (all annotations which use CV term, excluding "NOT" statements)      10
     involved_in | protein catabolic process      10
Spanning Tree (Parents/Children)
Only view relationship:
macromolecule metabolic process
 |__macromolecule catabolic process____________
 |__protein metabolic process__________________|
primary metabolic process                      |
 |__protein metabolic process__________________|
organonitrogen compound metabolic process      |
 |__protein metabolic process__________________|
 |__organonitrogen compound catabolic process__|
organic substance catabolic process            |
 |__macromolecule catabolic process____________|
 |__organonitrogen compound catabolic process__|
                                               protein catabolic process  408 rec.
                                                |__chaperone-mediated autophagy
                                                |   |__chaperone-mediated autophagy translocation complex assembly
                                                |   |__protein targeting to lysosome involved in chaperone-mediated autophagy
                                                |   |__regulation of chaperone-mediated autophagy(+)
                                                |__epidermal growth factor catabolic process
                                                |__glycoprotein catabolic process 7 rec.
                                                |   |__elastin catabolic process(+)
                                                |   |__mannoprotein catabolic process
                                                |   |__O-sialoglycoprotein catabolic process
                                                |   |__protein deglycosylation involved in glycoprotein catabolic process(+)
                                                |   |__proteoglycan catabolic process(+) 2 rec.
                                                |   |__ubiquitin-dependent glycoprotein ERAD pathway(+) 3 rec.
                                                |__hemoglobin catabolic process
                                                |__histone catabolic process
                                                |__insulin catabolic process 1 rec.
                                                |__lipoprotein catabolic process 1 rec.
                                                |   |__protein depalmitoleylation 1 rec.
                                                |   |__protein depalmitoylation
                                                |__low-density lipoprotein particle receptor catabolic process
                                                |   |__regulation of low-density lipoprotein particle receptor catabolic process(+)
                                                |__mitochondrial protein catabolic process 1 rec.
                                                |__prosthetic group catabolic process
                                                |__proteasomal protein catabolic process 293 rec.
                                                |   |__EGAD pathway
                                                |   |__ERAD pathway(+) 42 rec.
                                                |   |__proteasomal ubiquitin-independent protein catabolic process 1 rec.
                                                |   |__proteasome-mediated ubiquitin-dependent protein catabolic process(+) 250 rec.
                                                |   |__regulation of proteasomal protein catabolic process(+) 67 rec.
                                                |__protein catabolic process at synapse
                                                |   |__protein catabolic process at postsynapse
                                                |   |__protein catabolic process at presynapse
                                                |   |__protein catabolic process, modulating synaptic transmission
                                                |__protein catabolic process in the vacuole 3 rec.
                                                |   |__lysosomal protein catabolic process(+) 3 rec.
                                                |   |__regulation of protein catabolic process in the vacuole(+) 2 rec.
                                                |__protein denaturation
                                                |__proteolysis involved in protein catabolic process 391 rec.
                                                |   |__acrosome matrix dispersal
                                                |   |__mannoprotein catabolic process
                                                |   |__membrane protein proteolysis involved in retrograde protein transport, ER to cytosol
                                                |   |__modification-dependent protein catabolic process(+) 341 rec.
                                                |   |__proteasomal protein catabolic process 293 rec.
                                                |   |__protein quality control for misfolded or incompletely synthesized proteins(+) 6 rec.
                                                |   |__proteolysis associated with antigen processing and presentation(+)
                                                |   |__regulation of proteolysis involved in protein catabolic process(+) 81 rec.
                                                |   |__ubiquitin-independent protein catabolic process via the multivesicular body sorting pathway
                                                |__PSII associated light-harvesting complex II catabolic process
                                                |   |__regulation of PSII associated light-harvesting complex II catabolic process
                                                |__regulation of protein catabolic process 90 rec.
                                                |   |__negative regulation of protein catabolic process(+) 15 rec.
                                                |   |__positive regulation of protein catabolic process(+) 68 rec.
                                                |   |__regulation of chaperone-mediated autophagy(+)
                                                |   |__regulation of elastin catabolic process(+)
                                                |   |__regulation of low-density lipoprotein particle receptor catabolic process(+)
                                                |   |__regulation of membrane protein ectodomain proteolysis(+) 1 rec.
                                                |   |__regulation of proteasomal protein catabolic process(+) 67 rec.
                                                |   |__regulation of protein catabolic process at postsynapse, modulating synaptic transmission
                                                |   |__regulation of protein catabolic process at presynapse, modulating synaptic transmission
                                                |   |__regulation of protein catabolic process in the vacuole(+) 2 rec.
                                                |   |__regulation of PSII associated light-harvesting complex II catabolic process
                                                |__rhodopsin catabolic process
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Is a macromolecule catabolic process
protein metabolic process
organonitrogen compound catabolic process
Part of
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Synonyms
  • "cellular protein breakdown" EXACT
    "cellular protein catabolic process" EXACT
    "cellular protein catabolism" EXACT
    "cellular protein degradation" EXACT
    "multicellular organismal protein catabolic process" NARROW
    "pheromone catabolic process" RELATED
    "pheromone catabolism" RELATED
    "protein breakdown" EXACT
    "protein catabolism" EXACT
    "protein degradation" EXACT
Secondary IDs
hide External Crossreferences & Linkouts
Wikipedia:Protein_catabolism