FB2024_03 , released June 25, 2024
FB2024_03 , released June 25, 2024
CV Term Report
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General Information
Term proton-transporting V-type ATPase complex ID (Ontology) GO:0033176 (Gene Ontology)
Definition A proton-transporting two-sector ATPase complex that couples ATP hydrolysis to the transport of protons across a concentration gradient. The resulting transmembrane electrochemical potential of H+ is used to drive a variety of (i) secondary active transport systems via H+-dependent symporters and antiporters and (ii) channel-mediated transport systems. The complex comprises a membrane sector (V0) that carries out proton transport and a cytoplasmic compartment sector (V1) that catalyzes ATP hydrolysis. V-type ATPases are found in the membranes of organelles such as vacuoles, endosomes, and lysosomes, and in the plasma membrane.[ ISBN:0716743663 PubMed:16449553 ]
Also Known As "hydrogen-translocating V-type ATPase complex"
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Data Class Field Records
Genes (FBgn)  GO_BIOLOGICAL_PROCESS       6
Genes (FBgn)  GO_CELLULAR_COMPONENT      11
Genes (FBgn)  GO_MOLECULAR_FUNCTION       4
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 Genes
 proton-transporting V-type ATPase complex (all annotations which use CV term, excluding "NOT" statements)      11
     part_of | proton-transporting V-type ATPase complex      11
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membrane protein complex__
ATPase complex____________|
                          proton-transporting two-sector ATPase complex
                           |__proton-transporting V-type ATPase complex  41 rec.
                               |__plasma membrane proton-transporting V-type ATPase complex 17 rec.
                               |   |__plasma membrane proton-transporting V-type ATPase, V0 domain
                               |   |__plasma membrane proton-transporting V-type ATPase, V1 domain
                               |__proton-transporting V-type ATPase, V0 domain 19 rec.
                               |   |__plasma membrane proton-transporting V-type ATPase, V0 domain
                               |   |__vacuolar proton-transporting V-type ATPase, V0 domain(+) 18 rec.
                               |__proton-transporting V-type ATPase, V1 domain 14 rec.
                               |   |__plasma membrane proton-transporting V-type ATPase, V1 domain
                               |   |__vacuolar proton-transporting V-type ATPase, V1 domain(+) 12 rec.
                               |__vacuolar proton-transporting V-type ATPase complex 35 rec.
                                   |__lysosomal proton-transporting V-type ATPase complex(+)
                                   |__vacuolar proton-transporting V-type ATPase, V0 domain(+) 18 rec.
                                   |__vacuolar proton-transporting V-type ATPase, V1 domain(+) 12 rec.
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Is a proton-transporting two-sector ATPase complex
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Synonyms
  • "hydrogen-translocating V-type ATPase complex" EXACT
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