FB2024_03 , released June 25, 2024
FB2024_03 , released June 25, 2024
CV Term Report
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General Information
Term MKS complex ID (Ontology) GO:0036038 (Gene Ontology)
Definition A protein complex that is located at the ciliary transition zone and consists of several proteins some of which are membrane bound. Acts as an organiser of transition zone inner structure, specifically the Y-shaped links, in conjunction with the NPHP complex. The MKS complex also acts as part of the selective barrier that prevents diffusion of proteins between the ciliary cytoplasm and cellular cytoplasm as well as between the ciliary membrane and plasma membrane.[ PubMed:21422230 PubMed:21565611 PubMed:21725307 PubMed:22179047 PubMed:25869670 PubMed:26595381 PubMed:26982032 ]
Also Known As "MKS module"
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Annotations
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Data Class Field Records
Genes (FBgn)  GO_CELLULAR_COMPONENT       6
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 Full annotation statements 
Relevant FlyBase reports
 Gene Groups Genes
 MKS complex (all annotations which use CV term, excluding "NOT" statements)       1      6
     part_of | MKS complex       --       6
Spanning Tree (Parents/Children)
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cellular_component
 |__protein-containing complex__
cilium                          |
 |__ciliary transition zone_____|
cellular anatomical entity      |
 |__ciliary transition zone_____|
                                MKS complex  7 rec.
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Is a protein-containing complex
Part of ciliary transition zone
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Synonyms
  • "B9 complex" NARROW
    "MKS module" EXACT
    "TCTN-B9D complex" BROAD
    "tectonic complex" NARROW
    "tectonic-like complex" NARROW
Secondary IDs
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