FlyBase Aberration Report: Dmel\Df(3L)Pc-MK

General Information

Symbol

Df(3L)Pc-MK

Species

D. melanogaster

Name

Deficiency (3L) Polycomb

FlyBase ID

FBab0002339

Feature type

chromosomal_deletion

Also Known As

Df(3L)Pc^MK

Computed Breakpoints include

78A2;78C9

Features within 78A2--78C9

Sequence coordinates

Member of large scale dataset(s)

Nature of Aberration

Cytological Order

Progenitor

Mutagen

Class of aberration (relative to wild type)

chromosomal_deletion

(FlyBase, 2007)

Class of aberration (relative to progenitor)

chromosomal_deletion

(Levine et al., 1997, Duffy et al., 1996, Russell et al., 1996, Dorer et al., 1995, Harbecke and Lengyel, 1995, Pauli et al., 1995, Carpenter, 1994)

Breakpoints

78A2;78C9

(Levine et al., 1997, Russell et al., 1996, Carpenter, 1994)

78A3;79E1-79E2

(Duffy et al., 1996, Dorer et al., 1995, Harbecke and Lengyel, 1995, Pauli et al., 1995)

Causes alleles

Carries alleles

Transposon Insertions

Formalized genetic data

fng << bk1 << l(3)04063 << bk2 << l(3)j2C4

Genetic mapping information

Comments

Comments on Cytology

Right breakpoint of Df(3L)Pc-MK maps approximately 70kb proximal to the right breakpoint of Df(3L)Pc.

(Lin et al., 1996)

All limits from polytene analysis (FBrf0075380)

Sequence Crossreferences

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

Gene Deletion and Duplication Data

Genes Deleted / Disrupted

Complementation Data

Completely deleted / disrupted

Partially deleted / disrupted

Molecular Data

Completely deleted

Partially deleted

Genes NOT Deleted / Disrupted

Complementation Data

bet

(Spradling et al., 1999, BDGP Project Members, 1994-1999)

Csp

(Spradling et al., 1999, BDGP Project Members, 1994-1999)

fng

(Spradling et al., 1999, BDGP Project Members, 1994-1999)

Hem

(Spradling et al., 1999, BDGP Project Members, 1994-1999)

IleRS

(Spradling et al., 1999, BDGP Project Members, 1994-1999)

(Carpenter, 1994)

(Carpenter, 1994)

(Carpenter, 1994)

(Spradling et al., 1999, BDGP Project Members, 1994-1999)

l(3)07615

(Spradling et al., 1999, BDGP Project Members, 1994-1999)

l(3)j1B10

(BDGP Project Members, 1994-1999)

l(3)j2C4

(BDGP Project Members, 1994-1999)

l(3)neo29

(BDGP Project Members, 1994-1999)

l(3)S009720

(Szeged Stock Center, 1998-)

mia

(Lin et al., 1996, Lin, 1995.4.19)

mub

(Spradling et al., 1999, BDGP Project Members, 1994-1999)

Oct-TyrR

(Spradling et al., 1999, BDGP Project Members, 1994-1999)

rgn

(BDGP Project Members, 1994-1999)

RpLP0

(Spradling et al., 1999, BDGP Project Members, 1994-1999)

skd

(Spradling et al., 1999, BDGP Project Members, 1994-1999)

Su(Tpl)

(Dorer et al., 1995)

Ten-m

(Spradling et al., 1999, BDGP Project Members, 1994-1999)

Molecular Data

Genes Duplicated

Complementation Data

Completely duplicated

Partially duplicated

Molecular Data

Completely duplicated

Partially duplicated

Genes NOT Duplicated

Complementation Data

Molecular Data

Affected Genes Inferred by Location

Related Comments

Phenotypic Data

In combination with other aberrations

Df(3L)Pc-MK/Df(3L)Pc-cp2 animals carrying Pc^tPa develop into normal looking larvae which fail to hatch. Larvae removed from the vitelline membrane are immobile, but respond to pokes from a needle with slow, uncoordinated movements. The larval muscle pattern is indistinguishable from wild-type. The SNb nerve ends at muscle VO1, failing to innervate the VL1 muscles. RP3 motor axons fail to innervate muscle VL3 and VL4.

(Hartmann et al., 1997)

NOT in combination with other aberrations

Approximately 83% of heterozygous males have ectopic sex combs on the second and/or third legs, indicating a transformation towards first leg.

(Zorin et al., 1999)

Weak second site non-complementing phenotype with zip^Ebr and zip^mhc-c6.1 : malformed phenotype penetrance 10-24%.

(Halsell and Kiehart, 1998)

Initially showed maternal enhancement of dpp^hr4, but effect not due to disruption of discrete element within the deficiency. The enhancing activity seems to be recombinationally separable from the deficiency.

(Nicholls and Gelbart, 1998)

Acts as a dosage sensitive maternal modifier of run : causes tergite defects in greater than 50% of run³ heterozygotes.

(Duffy et al., 1996)

Fails to form a 78C puff.

(Russell et al., 1996)

Deficient embryos show an uninterpretable mutant midgut phenotype.

(Bilder and Scott, 1995)

Mutation changes the level of w expression in ph-p^lac+3 flies; eye colour is darker.

(Fauvarque et al., 1995)

Heterozygosity for this deletion suppresses the mutant ovarian phenotype of ovo^D2.

(Pauli et al., 1995)

Stocks (1)

Kyoto

106817

Df(3L)Pc-MK/TM3, Sb¹ Ser¹

Notes on Origin

Discoverer

Denell.

Balancer / Genotype Variants of the Aberration

Separable Components

Other Comments

"78A2;78C9" was stated as revision.

(Russell et al., 1996, Carpenter, 1994)

Synonyms and Secondary IDs (8)

Reported As

Symbol Synonym

Df(3)Pc-MK

(Sen et al., 2015)

Df(3L)PC-MK

(Mathe et al., 2003)

Df(3L)Pc-MK

(Kugler et al., 2011, Ueno and Kidokoro, 2008, Crest et al., 2007, Riparbelli and Callaini, 2007)

Df(3L)Pc-Mk

(Müller et al., 2005, Zorin et al., 1999, Carrera et al., 1998, Hartmann et al., 1997, Harbecke and Lengyel, 1995)

Df(3L)Pc^MK

(Brumby et al., 2004, Levine et al., 1997, Levine et al., 1994, Sato and Denell, 1985)

Df(3L)PcMk

(Muñoz-Soriano and Paricio, 2007)

Df(3L)pc-MK

(Pesah et al., 2004)

Name Synonyms

Deficiency (3L) Polycomb

Secondary FlyBase IDs

References (47)

Report Sections

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