FlyBase Aberration Report: Dmel\Df(3L)lxd6

FB2024_02 , released April 23, 2024

FB2024_02 , released April 23, 2024

Aberration: Dmel\Df(3L)lxd6

General Information

Symbol

Df(3L)lxd6

Species

D. melanogaster

Name

Deficiency (3L) low xanthine dehydrogenase

FlyBase ID

FBab0002387

Feature type

chromosomal_deletion

Also Known As

Df(3L)lxd⁶, Df(3L)1xd6

Computed Breakpoints include

67E5-67E7;68B2-68B4

Features within 67E5--68B4

Sequence coordinates

Member of large scale dataset(s)

Nature of Aberration

Cytological Order

Progenitor

Mutagen

(Schott et al., 1986)

Class of aberration (relative to wild type)

chromosomal_deletion

(FlyBase, 2007)

Class of aberration (relative to progenitor)

chromosomal_deletion

(Cook, 2002.2.25, Mogila, 1998.3.19, Coyne, 1996, Duffy et al., 1996, Phillips and Shearn, 1990, Schott et al., 1986)

Breakpoints

[];[]

(Schott et al., 1986)

67E1-67E2;68C1-68C2

(Mogila, 1998.3.19, Coyne, 1996, Duffy et al., 1996, Phillips and Shearn, 1990)

67E5-67E7;68B2-68B4

(Cook, 2002.2.25)

Causes alleles

Carries alleles

Transposon Insertions

Formalized genetic data

can << bk1 << hay << grr << bk2 << Sgs3

Genetic mapping information

Comments

Comments on Cytology

Ref: FBrf0043787.

(Phillips and Shearn, 1990)

All limits from polytene analysis (Cook, 2002.2.23, pers comm)

Sequence Crossreferences

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

Gene Deletion and Duplication Data

Genes Deleted / Disrupted

Complementation Data

Completely deleted / disrupted

(Phillips and Shearn, 1990)

(Mogila, 1998.3.19)

(Regan and Fuller, 1988)

(Crosby and Meyerowitz, 1986)

(Crosby and Meyerowitz, 1986)

(Crosby and Meyerowitz, 1986)

(Crosby and Meyerowitz, 1986)

(Crosby and Meyerowitz, 1986)

(Crosby and Meyerowitz, 1986)

(Crosby and Meyerowitz, 1986)

(Crosby and Meyerowitz, 1986)

(Crosby and Meyerowitz, 1986)

(Crosby and Meyerowitz, 1986)

(Crosby and Meyerowitz, 1986)

(Crosby and Meyerowitz, 1986)

(Crosby and Meyerowitz, 1986)

(Szeged Stock Center, 1998-)

(Crosby and Meyerowitz, 1986, Schott et al., 1986)

(Crosby and Meyerowitz, 1986, Schott et al., 1986)

(Brumby et al., 2004)

(Spradling et al., 1999)

(Schott et al., 1986)

(Szeged Stock Center, 1998-)

(Bartscherer et al., 2006)

Partially deleted / disrupted

Molecular Data

Completely deleted

(Zhang et al., 2003)

Partially deleted

Genes NOT Deleted / Disrupted

Complementation Data

Molecular Data

Genes Duplicated

Complementation Data

Completely duplicated

Partially duplicated

Molecular Data

Completely duplicated

Partially duplicated

Genes NOT Duplicated

Complementation Data

Molecular Data

Affected Genes Inferred by Location

Related Comments

Phenotypic Data

In combination with other aberrations

Df(3L)lxd6/Df(3L)vin4 transheterozygotes show the same head involution defects as Df(3L)vin4 homozygotes.

(Scuderi et al., 2006)

NOT in combination with other aberrations

Df(3L)lxd6 flies develop show no visible phenotype.

(Scuderi et al., 2006)

The Df(3L)lxd6 chromosome does not act as a dominant suppressor of telomeric silencing (assayed using the effect of the chromosome on the eye colour phenotype of flies carrying "P{w^var}KR3-2", a stable "brown-red" variant of the P{3'WP-2,w^var}2Lt insertion).

(Mason et al., 2004)

Heterozygosity for Df(3L)lxd6 results in 0.4% X chromosome nondisjunction and 0.0% fourth chromosome nondisjunction in In(1)FM7/X ; sv^spa-pol females.

(Harris et al., 2003)

Does not cause unconditional lethality in hybrid females when heterozygous with D.simulans chromosome.

(Coyne et al., 1998)

No second site non-complementing phenotype with zip^Ebr and zip^mhc-c6.1.

(Halsell and Kiehart, 1998)

Dominantly causes tergite defects in less than 50% of run³ heterozygotes.

(Duffy et al., 1996)

Mutation does not affect the level of w expression in ph-p^lac+3 flies.

(Fauvarque et al., 1995)

Male sterile when heterozygous with hay^nc2.

(Regan and Fuller, 1988)

Homozygous lethal.

(Schott et al., 1986)

Stocks (2)

89

y¹; Df(3L)lxd6/TM3, Sb¹ Ser¹

105726

y^1?; Df(3L)lxd6/TM3, Sb¹ Ser¹

Notes on Origin

Discoverer

Balancer / Genotype Variants of the Aberration

Separable Components

Other Comments

"67E5--7;68B2--4" was stated as revision.

(Cook, 2002.2.25)

Used in D.melanogaster/D.simulans hybrids to map at least four non-overlapping regions on the D.simulans 3R that have effects on the species difference of cuticular hydrocarbon profile.

(Coyne, 1996)

Synonyms and Secondary IDs (8)

Reported As

Symbol Synonym

Df(3L)1xd6

(Crest et al., 2007, Firth et al., 2000, Spradling et al., 1999)

Df(3L)Ixd6

(Harris et al., 2003)

Df(3L)Lxd6

(Kon et al., 2005)

Df(3L)lxd6

(Monribot-Villanueva et al., 2013, Goodliffe et al., 2007, Kim et al., 2007, Bartscherer et al., 2006, Scuderi et al., 2006, Wilson et al., 2006, He et al., 2005)

Df(3L)lxd⁶

(Kuhfittig et al., 2001, LaJeunesse and Shearn, 1996, Fauvarque et al., 1995, Phillips and Shearn, 1990, Crosby and Meyerowitz, 1986, Fuller, 1986)

lxd6

(ffrench-Constant and Roush, 1991)

lxd⁶

(Schott et al., 1986)

Name Synonyms

Deficiency (3L) low xanthine dehydrogenase

Secondary FlyBase IDs

References (49)

Report Sections