Testes from Dp(3;2)ry+; Df(3R)kar5l males heterozygous with wrl1 exhibit defects in axoneme structure identical to wrl1 homozygotes and are sterile. Heterozygotes with wild type exhibit an identical testis phenotype so are also sterile as the seminal vesicles contain only a few motile sperm. Haploinsufficient for male fertility; βTub85Dn dominantly suppresses this sterility.
Dp(3;2)ry+; Df(3R)kar3J homozygotes viable (Ish-Horowicz) Dp(3;2)ry+; Df(3R)kar3J/Df(3R)kar3l viable (Ish-Horowicz) Dp(3;2)ry+; Df(3R)kar3J/Df(3R)kar3l female sterile (Ish-Horowicz) Dp(3;2)ry+; Df(3R)karSz29/Df(3R)kar3J female fertile (Ish-Horowicz)
Flies show enhanced mutant fused phenotypes, acting through Su(fu).
Double heterozygotes with wrl1 exhibit defects in axoneme organization.
The Dp(3;2)ry+; Df(3R)kar5l combination was named Df(3R)wrl in the paper as the synthetic deficiency removed wrl.