FB2024_03 , released June 25, 2024
Aberration: Dmel\Df(1)frqdel3
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General Information
Symbol
Df(1)frqdel3
Species
D. melanogaster
Name
FlyBase ID
FBab0046231
Feature type
chromosomal_deletion
Computed Breakpoints include
Features within 16F7--17A2 (Estimated cytology)
Genomic Maps
Sequence coordinates
X:18,137,670..18,137,670 (Df(1)frq[del3]:bk1)
(Dason et al., 2009)
X:18,191,475..18,191,475 (Df(1)frq[del3]:bk2)
(Dason et al., 2009)
Member of large scale dataset(s)
Nature of Aberration
Cytological Order
Progenitor
PBac{WH}Frq2f06131
(Dason et al., 2009)
P{XP}d04472
(Dason et al., 2009)
Mutagen
FLPase
(Dason et al., 2009)
Class of aberration (relative to wild type)
chromosomal_deletion
(Dason et al., 2009)
Class of aberration (relative to progenitor)
chromosomal_deletion
(Dason et al., 2009)
Breakpoints
Causes alleles
Frq2del3
(Dason et al., 2009)
Carries alleles
Transposon Insertions
Formalized genetic data
Genetic mapping information
Comments

Scer\FRT-mediated recombination between the two progenitor insertions has resulted in the deletion of the genomic sequence between them.

(Dason et al., 2009)
Comments on Cytology
Sequence Crossreferences
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
Gene Deletion and Duplication Data
Genes Deleted / Disrupted
Complementation Data
Completely deleted / disrupted
Partially deleted / disrupted
Molecular Data
Completely deleted
Andorra
(Dason et al., 2009)
Frq1
(Dason et al., 2009)
Partially deleted
Frq2
(Dason et al., 2009)
Genes NOT Deleted / Disrupted
Complementation Data
 
Molecular Data
 
Genes Duplicated
Complementation Data
Completely duplicated
Partially duplicated
Molecular Data
Completely duplicated
Partially duplicated
Genes NOT Duplicated
Complementation Data
 
Molecular Data
 
Affected Genes Inferred by Location (5)
Phenotypic Data
In combination with other aberrations

Df(1)frqdel3/Df(1)frqdel1 third instar larval mutants do not show any significant difference in resting Ca[2+] level compared to controls.

(Dason et al., 2009)

Df(1)frqdel3/Df(1)frqdel1 third instar larval mutants exhibit more severe defects in quantal release in low-Ca[2+] saline (65% reduction) than in high-Ca[2+] saline (35% reduction).

(Dason et al., 2009)

Nerve-terminals of Df(1)frqdel3/Df(1)frqdel1 third instar larvae show significantly more 1s boutons than in wild-type. The number of 1s and 1b boutons is not different in Df(1)frqdel3 mutants compared to wild-type. Nerve-evoked compound EJPs are significantly smaller than for controls. The frequency and amplitude of spontaneous release are not affected in Df(1)frqdel3/Df(1)frqdel1 lines.

(Dason et al., 2009)

Peak amplitudes of Ca[2+] signals are significnatly reduced by 15% on average in Df(1)frqdel3/Df(1)frqdel1 third instar larval mutants compared to controls.

(Dason et al., 2009)
NOT in combination with other aberrations

Nerve-terminals of Df(1)frqdel3 third instar larvae show significantly more 1s boutons than in wild-type. The number of 1s and 1b boutons is not different in Df(1)frqdel3 mutants compared to wild-type. Nerve-evoked compound EJPs are significantly smaller than for controls. The frequency and amplitude of spontaneous release are not affected in Df(1)frqdel3 mutants. The number of quanta released by single 1b and 1s boutons is significantly reduced in Df(1)frqdel3 mutants in comparison with controls. No differences in amplitude or time course of spontaneously occurring quantal events are found.

Df(1)frqdel1 third instar larval mutants exhibit more severe defects in quantal release in low-Ca[2+] saline (65% reduction) than in high-Ca[2+] saline (35% reduction).

Df(1)frqdel1 third instar larval mutants do not show any significant difference in resting Ca[2+] level compared to controls.

Peak amplitudes of Ca[2+] signals are significnatly reduced by 15% on average in Df(1)frqdel3 third instar larval mutants compared to controls.

(Dason et al., 2009)
Stocks (0)
Notes on Origin
Discoverer
 
Balancer / Genotype Variants of the Aberration
 
Separable Components
 
Other Comments
 
Synonyms and Secondary IDs (3)
Reported As
Symbol Synonym
Df(1)frqdel3
Df(X)frqdel3
frqdel3
(Dason et al., 2009)
Name Synonyms
Secondary FlyBase IDs
    References (1)