Excision of the progenitor insertion (P{GAL4}4C) resulting in a deletion of 632 bp.

Df(2R)F4 homozygosity leads to short lived females and long lived males, as compared to controls. Females exhibit decreased resistance to desiccation and their guts show increased numbers of enterocytes (in both 7-days and 40-days old individuals), increased mitotic index and increased numbers of intestinal stem cells, but decreased ploidy/endoreplication, as compared to controls.