FB2024_03 , released June 25, 2024
Allele: Dmel\abd-AP10
Open Close
General Information
Symbol
Dmel\abd-AP10
Species
D. melanogaster
Name
FlyBase ID
FBal0000085
Feature type
allele
Associated gene
Dmel\abd-A
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
X ray
Progenitor genotype
Caused by aberration
Tp(3;2)iab2P10
Cytology
Description

Lesion mapped to: 35-36 kb.

(Karch et al., 1990)

Mutations in the transcription unit: breakpoints map to the extremes of the transcription unit (FBrf0042053).

(Macias et al., 1990)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Heterozygous females show a significant increase in the level of monoene cuticular hydrocarbons and a significant decrease in the level of 7,11-diene cuticular hydrocarbons compared to wild-type females.

      (Wicker-Thomas and Jallon, 2001)

      First instar larvae exhibit lateral dots (a paired structure found in A1 segment of wild type) in abdominal segment A2 and rarely in A3.

      (Jijakli and Ghysen, 1992)

      Homozygous embryos transform parasegment 7--13 into parasegment 6.

      (Sanchez-Herrero, 1991)

      Segment-dependent graded phenotype related to level of abd-A protein expression (FBrf0039775). A reduction in abd-A product but more than in abd-AMX2. Dimunition of product is not uniform, shows a gradient across segments.

      (Macias et al., 1990)

      Hemizygous epidermal cell clones show partial adult transformation. The moderate phenotype indicates the presence of some abd-A product.

      (Busturia et al., 1989)

      The frequency of variegated bithorax transformations seen in Df(3R)red-P52 heterozygotes is not increased in flies also containing a copy of abd-AP10.

      (Capdevila and Garcia-Bellido, 1981)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (4)
      Notes on Origin
      Discoverer

      N. Shaw, 1974.

      Comments
      Comments

      Presents a gradient towards the posterior of abd-A expression in epidermis and ventral nerve cord.

      (Sanchez-Herrero, 1991)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      abd-AP10
      (Monedero Cobeta et al., 2017, Karlsson et al., 2010)
      iab2P10
      (Karch et al., 1990)
      Name Synonyms
      Secondary FlyBase IDs
        References (9)