Polytene chromosomes normal.
lethal | pharate adult stage P15 (with Pfas3)
lethal | prepupal stage P2 (with Pfas3)
lethal | pupal stage P5 (with Pfas3)
ade24/Df(2L)ED343 animals show some lethality during the pupal stage and a low proportion of the pupae contain necrotic tissue.
Auxotroph for purine. Reduced wing size, deranged posterior wing margins and extra wing veins. Bristles are thinner and sometimes reduced in size.
Pfas4/Df(2L)ED343 has partially lethal - majority die | pupal stage phenotype, suppressible | partially by BacA\p35UAS.cHa
Pfas4/Df(2L)ED343 has melanotic necrosis | pupal stage P5 phenotype, suppressible by BacA\p35UAS.cHa
BacA\p35Scer\UAS.cHa (in the absence of a Scer\GAL4 driver) partially suppresses the lethality and almost completely suppresses the necrotic phenotype of ade24/Df(2L)ED343 and Prat12A19/Df(3R)dsx43 animals.
Exhibit purine autotrophy and defective FGARAT (EC 6.33.5.3) enzyme. Weak allele.