FB2024_03 , released June 25, 2024
Allele: Dmel\dec2
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General Information
Symbol
Dmel\dec2
Species
D. melanogaster
Name
FlyBase ID
FBal0002325
Feature type
allele
Associated gene
Dmel\dec
Associated Insertion(s)
Carried in Construct
Also Known As
fs(1)384
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ethyl methanesulfonate
(Komitopoulou et al., 1988)
Progenitor genotype
Cytology
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Main body and appendages have few large clumps of endochorionic material replacing the elaborate network of modified pillars. Phenotype suggests a disruption, not reduction, in amplification of the chorion genes Cp15, Cp16, Cp18, Cp19, Cp36 and Cp38.

      (Komitopoulou et al., 1988)

      Functional defect in the follicle cells.

      (Perrimon and Gans, 1983)

      Homozygous females produce eggs in which the two dorsal appendages are much reduced or absent. The chorion usually appears abnormal and vacuolated, and the eggs are collapsed. Mosaic analysis experiments produce eggs with patches of mutant chorion.

      (Wieschaus et al., 1981)

      protein products absent

      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Not rescued by

      dec2 is not rescued by decfc177TAAG

      (Mauzy-Melitz and Waring, 2003)
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (2)
      Notes on Origin
      Discoverer
      Comments
      Comments

      Eggs from homozygous females take up dye when laid on medium containing neutral red. Germ line clonal analysis shows that dec-1 function is required in the soma.

      (Wieschaus et al., 1981)

      The structure of the innermost chorionic layer of dec-12 mutants has been studied using electron microscopy.

      (Margaritis et al., 1991)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (6)
      References (10)