FB2024_03 , released June 25, 2024
Allele: Dmel\fw34e
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General Information
Symbol
Dmel\fw34e
Species
D. melanogaster
Name
FlyBase ID
FBal0004903
Feature type
allele
Associated gene
Dmel\fw
Associated Insertion(s)
?{}fw34e
Carried in Construct
Key Links
Genomic Maps

Allele class

hypomorphic allele - genetic evidence

Mutagen
Nature of the Allele
Allele class

hypomorphic allele - genetic evidence

(Leshko-Lindsay and Corces, 1997)
Mutagen
spontaneous
(Leshko-Lindsay and Corces, 1997)
Progenitor genotype
Associated Insertion(s)
?{}fw34e
Cytology
Description

Insertion of a transposable element.

(Leshko-Lindsay and Corces, 1997)
Mutations Mapped to the Genome
Curation Data
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Mild defects in eye morphology. Defects in the development of the mechanosensory bristles including the macrochaetae, microchaetae and bristles surrounding the eye. Shortened head and scutellum. fw34e/Df(1)KA10 transheterozygotes do not produce any viable adult females, female lethal phase occurs in the pupal stages.

      (Leshko-Lindsay and Corces, 1997)

      Originally showed eye surface medium folded; bristles much gnarled. Schultz and Curry report that stock in 1940 showed gnarled bristles and eye small but no vertical fold. RK2.

      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Rescued by

      fw34e is rescued by fw+t12.7

      (Leshko-Lindsay and Corces, 1997)
      Comments

      Eye and bristle defects of homozygous adults are rescued by fw+t12.7.

      (Leshko-Lindsay and Corces, 1997)
      Images (1)
      Stocks (2)
      Notes on Origin
      Discoverer

      Duncan, 20th May 1934.

      Comments
      Comments

      Allele is haploinsufficient.

      (Leshko-Lindsay and Corces, 1997)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      fw34e
      (Popodi et al., 2010-)
      Name Synonyms
      Secondary FlyBase IDs
        References (4)