FB2024_03 , released June 25, 2024
Allele: Dmel\mei-9D3
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General Information
Symbol
Dmel\mei-9D3
Species
D. melanogaster
Name
FlyBase ID
FBal0012178
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Genomic Maps

Allele class
Nature of the Allele
Allele class
Progenitor genotype
Cytology
Description

Deletion of nucleotides 553-558, resulting in an in frame deletion of two conserved residues (V143 and K144) at the beginning of helicase-like motif III.

Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Comment:

Position of mutation on reference sequence inferred by FlyBase curator based on author statement: Deletion of nucleotides 553-558, resulting in an in frame deletion of two conserved residues (V143 and K144) at the beginning of helicase-like motif III. (adjusted for additional 43 residues at N terminus in annotated protein relative to reported protein).

Variant Molecular Consequences
Associated Sequence Data
DNA sequence
Protein sequence
 
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

Hemizygous male larvae are sensitive to HN2 and MMS. Homozygous females produce diplo-X and nullo-X exceptions at roughly the same frequency.

mutagen sensitive reduces exchange

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer

The lesion in mei-9D2 and in mei-9D3 is identical.

External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (1)
Reported As
Symbol Synonym
mei-9D3
Name Synonyms
Secondary FlyBase IDs
    References (4)