FB2024_03 , released June 25, 2024
Allele: Dmel\nkd4
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General Information
Symbol
Dmel\nkd4
Species
D. melanogaster
Name
FlyBase ID
FBal0013026
Feature type
allele
Associated gene
Dmel\nkd
Associated Insertion(s)
Carried in Construct
Also Known As
nkd9G33
Key Links
Genomic Maps

Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ethyl methanesulfonate
(Tearle and Nusslein-Volhard, 1987)
Progenitor genotype
Cytology
Description

Nucleotide substitution: C?T.

(Waldrop et al., 2006)

Amino acid replacement: R517term.

(Waldrop et al., 2006)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
point_mutation
3L:19,006,712..19,006,712 [-]
Nucleotide change:

C19006712T

Reported nucleotide change:

C?T

Amino acid change:

R518term | nkd-PA

Reported amino acid change:

R517term

(Waldrop et al., 2006)
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      No eye bristle phenotype is seen in mutant eyes.

      (Rousset et al., 2001)

      Homozygous embryos have a moderate cuticle phenotype.

      (Zeng et al., 2000)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Other
      Statement
      Reference

      hry1, nkd4 has visible | somatic clone phenotype

      (Zeng et al., 2000)
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      nkd4 h1 clones give rise to a rough eye phenotype and loss of wing margin bristles.

      (Zeng et al., 2000)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (1)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      nkd4
      nkd9G33
      (Waldrop et al., 2006, Rousset et al., 2001, Zeng et al., 2000)
      nkd9G
      (Tearle and Nusslein-Volhard, 1987)
      Name Synonyms
      Secondary FlyBase IDs
        References (5)