FlyBase Allele Report: Dmel\ovo[svb-2]

General Information

Symbol

Dmel\ovo^svb-2

Species

D. melanogaster

Name

FlyBase ID

FBal0013438

Feature type

allele

Associated gene

Dmel\ovo

Associated Insertion(s)

Carried in Construct

Also Known As

svb^YP17b, svb²

Key Links

Allele class

Mutagen

ethyl methanesulfonate

Nature of the Allele

Allele class

Mutagen

ethyl methanesulfonate

(Garfinkel et al., 1992)

Progenitor genotype

Cytology

Description

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

lethal

(Lindsley and Zimm, 1992, Oliver et al., 1987)

lethal | recessive

(Perrimon et al., 1989)

Phenotype Manifest In

denticle

(Tanaka et al., 2000)

denticle | ectopic

(Payre et al., 1999)

embryonic epidermis

(Payre et al., 1999)

ventral denticle belt

(Payre et al., 1999)

Detailed Description

Statement

Reference

Fails to complement the Dsec\ovo in D.melanogaster/D.sechellia hybrids.

(Sucena and Stern, 2000)

Mutant embryos develop normally except that they have denticle with reduced number and size (the remaining denticles have a dot-like morphology).

(Tanaka et al., 2000)

Expression of ovo^Scer\UAS.cPa driven by Scer\GAL4^ptc-559.1 in a ovo^svb-2 background also produces ectopic denticles. Ectopic denticles produced by ubiquitous expression of spi^s.Scer\UAS (driven by Scer\GAL4^e22c or Scer\GAL4^69B) are suppressed in ovo^svb-2 embryos.

(Payre et al., 1999)

Phenotypic category: ovo⁺ svb^-.

(Garfinkel et al., 1992)

Phenotypic category: ovo⁺.

(Lindsley and Zimm, 1992)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Suppressor of

Statement

Reference

ovo^svb-2 is a suppressor of denticle | ectopic phenotype of Scer\GAL4^e22c, pan^ΔN.UAS

(Payre et al., 1999)

ovo^svb-2 is a suppressor of embryonic epidermis phenotype of Scer\GAL4^e22c, spi^s.UAS

(Payre et al., 1999)

ovo^svb-2 is a suppressor of denticle | ectopic phenotype of Scer\GAL4^e22c, spi^s.UAS

(Payre et al., 1999)

ovo^svb-2 is a suppressor of embryonic epidermis phenotype of Scer\GAL4^69B, spi^s.UAS

(Payre et al., 1999)

ovo^svb-2 is a suppressor of denticle | ectopic phenotype of Scer\GAL4^69B, spi^s.UAS

(Payre et al., 1999)

ovo^svb-2 is a suppressor of embryonic epidermis phenotype of wg^l-17

(Payre et al., 1999)

ovo^svb-2 is a suppressor of ventral denticle belt phenotype of wg^l-17

(Payre et al., 1999)

Additional Comments

Genetic Interactions

Statement

Reference

wg^l-17, ovo^svb-2 double mutant embryos produce naked cuticle, with some residual abortive denticles. This phenotype is characteristic of ovo^svb-2 embryos. pan^ΔN.Scer\UAS driven ubiquitously by Scer\GAL4^e22c produces ectopic denticles. Addition of ovo^svb-2 in this background suppresses both normal and pan^ΔN.Scer\UAS induced denticles, producing mostly naked cuticle.

(Payre et al., 1999)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Not rescued by

ovo^svb-2 is not rescued by ovo^OW10.0

(Garfinkel et al., 1992)

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

Bloomington

816

w¹ ovo^svb-2/FM7c, sn⁺

Notes on Origin

Discoverer

Comments

Maternal germline clonal analysis demonstrates there is no maternal effect.

(Perrimon et al., 1989)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (5)

Reported As

Symbol Synonym

ovo^svb-2

(Popodi et al., 2010-)

svb²

(Rizzo and Bejsovec, 2017, Andrew and Baker, 2008, Galindo et al., 2007, Sucena and Stern, 2000, Payre et al., 1999)

svb^YP17B

(Garfinkel et al., 1992)

svb^YP17b

(Schock et al., 2000, Tanaka et al., 2000, Rulifson et al., 1996, Perrimon et al., 1989, Oliver et al., 1987)

svb^yp17

(Grinblat et al., 1994)

Name Synonyms

Secondary FlyBase IDs

References (15)

Report Sections

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