FB2024_03 , released June 25, 2024
Allele: Dmel\Pgdn39
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General Information
Symbol
Dmel\Pgdn39
Species
D. melanogaster
Name
FlyBase ID
FBal0013690
Feature type
allele
Associated gene
Dmel\Pgd
Associated Insertion(s)
Carried in Construct
Also Known As
Pgd39, l(1)39
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ethyl methanesulfonate
(Lindsley and Zimm, 1992, Gvozdev et al., 1977, Gvozdev et al., 1975, Gvozdev et al., 1973)
Progenitor genotype
PgdA
(Lindsley and Zimm, 1992)
Cytology
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 1 )
      Disease
      Interaction
      References
      ameliorates  myofibrillar myopathy 2
      modeled by Hsap\CRYABR120G.UAS
      (Xie et al., 2013)
      Comments on Models/Modifiers Based on Experimental Evidence ( 1 )
       

      Pgdn39/Zwlo2a in transheterozygous combination ameliorates the Hsap\CRYABR120G.UAS 'myofibrillar myopathy 2' model.

      (Xie et al., 2013)
      Disease-implicated variant(s)
       
      Phenotypic Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressor of
      Statement
      Reference

      Zw[+], G6pdlo2a, Pgdn39, Pgd[+] is a suppressor | partially of visible | adult stage phenotype of Hsap\CRYABR120G.UAS, Scer\GAL4GMR.PF

      (Xie et al., 2013)
      Phenotype Manifest In
      Suppressor of
      Statement
      Reference

      Zw[+], G6pdlo2a, Pgdn39, Pgd[+] is a suppressor | partially of eye phenotype of Hsap\CRYABR120G.UAS, Scer\GAL4GMR.PF

      (Xie et al., 2013)
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (0)
      Mutant
      Wild-type
      Stocks (8)
      Notes on Origin
      Discoverer

      Gvozdev.

      (Lindsley and Zimm, 1992)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (6)
      References (11)