FB2024_03 , released June 25, 2024
Allele: Dmel\ras2
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General Information
Symbol
Dmel\ras2
Species
D. melanogaster
Name
FlyBase ID
FBal0014404
Feature type
allele
Associated gene
Dmel\ras
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
spontaneous
(Slee and Bownes, 1995, Nash et al., 1994)
Progenitor genotype
Cytology
Description

Restriction pattern variant in the 1.1kb XhoI fragment that includes the 5' portion of the ras coding region, exons 1, 2 and part of exon 3. An approximately 5.0kb insert contains an EcoRI site but neither XhoI nor HindIII sites.

(Nash et al., 1994)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Eye colour: dark ruby.

      (Zhimulev et al., 1987)

      Eye colour: dark red. Dark red eye colour attributable to a pyrimidine deficiency.

      (Nash et al., 1981)

      Eyes contain 15% normal red pigment and 103% normal brown pigment.

      (Nolte, 1959)

      Eye colour: translucent ruby, lighter than ras1 and darkens less with age.

      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      NOT suppressed by
      Statement
      Reference

      ras2 has phenotype, non-suppressible by su(Hw)2

      (Lindsley and Grell, 1968)
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments
      Images (2)
      Stocks (10)
      Notes on Origin
      Discoverer

      Grossman, 1932.

      Comments
      Comments

      Strong ras mutant.

      (Nash et al., 1981)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (1)
      Reported As
      Symbol Synonym
      ras2
      (Popodi et al., 2010-, Cook et al., 2009.2.28)
      Name Synonyms
      Secondary FlyBase IDs
        References (10)