FlyBase Allele Report: Dmel\sc[A]

General Information

Symbol

Dmel\sc^A

Species

D. melanogaster

Name

of Agol

FlyBase ID

FBal0015225

Feature type

allele

Associated gene

Dmel\sc

Associated Insertion(s)

Carried in Construct

Key Links

Allele class

Mutagen

Nature of the Allele

Allele class

Mutagen

Progenitor genotype

Caused by aberration

In(1)sc^A

Cytology

Description

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

partially lethal - majority die

(Lindsley and Zimm, 1992)

partially lethal - majority die | recessive

(Agol, 1936)

visible

(Mari-Beffa et al., 1991)

visible, with Scer\GAL4^pnr-MD237, sc^UAS.cPa

(de Navascués and Modolell, 2010)

Phenotype Manifest In

chaeta

(Mari-Beffa et al., 1991)

scutellar bristle | increased number, with Scer\GAL4^pnr-MD237, sc^UAS.cPa

(de Navascués and Modolell, 2010)

tergite

(Mari-Beffa et al., 1991)

Detailed Description

Statement

Reference

Overexpression of sc^Scer\UAS.cPa under the control of Scer\GAL4^pnr-MD237 in a homozygous sc^A mutant background is a potent bristle inducer.

(de Navascués and Modolell, 2010)

Similar to sc. Viability low. RK2A.

(Lindsley and Zimm, 1992)

Homozygous females show a strong loss of tergite chaetae.

(Mari-Beffa et al., 1991)

Homozygous females have low viability.

(Agol, 1936)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Enhanced by

Statement

Reference

Scer\GAL4^pnr-MD237, sc^A, sc^UAS.cPa has visible phenotype, enhanceable by Chi^E

(de Navascués and Modolell, 2010)

Scer\GAL4^pnr-MD237, sc^A, sc^UAS.cPa has visible phenotype, enhanceable by tup^RNAi.UAS/Scer\GAL4^pnr-MD237

(de Navascués and Modolell, 2010)

sc^A has visible phenotype, enhanceable by Df(1)sc19

(Mari-Beffa et al., 1991)

sc^A has visible phenotype, enhanceable by Df(1)260-1

(Mari-Beffa et al., 1991)

Suppressor of

Statement

Reference

sc^A is a suppressor of visible phenotype of Scer\GAL4^pnr-MD237, tup^RNAi.UAS

(de Navascués and Modolell, 2010)

Phenotype Manifest In

Enhanced by

Statement

Reference

Scer\GAL4^pnr-MD237, sc^A, sc^UAS.cPa has scutellar bristle | increased number phenotype, enhanceable by Chi^E

(de Navascués and Modolell, 2010)

Scer\GAL4^pnr-MD237, sc^A, sc^UAS.cPa has scutellar bristle | increased number phenotype, enhanceable by tup^RNAi.UAS/Scer\GAL4^pnr-MD237

(de Navascués and Modolell, 2010)

sc^A has chaeta phenotype, enhanceable by Df(1)sc19

(Mari-Beffa et al., 1991)

sc^A has tergite phenotype, enhanceable by Df(1)sc19

(Mari-Beffa et al., 1991)

sc^A has chaeta phenotype, enhanceable by Df(1)260-1

(Mari-Beffa et al., 1991)

sc^A has tergite phenotype, enhanceable by Df(1)260-1

(Mari-Beffa et al., 1991)

Suppressor of

Statement

Reference

sc^A is a suppressor of scutellar bristle | increased number | somatic clone phenotype of tup^ex4

(de Navascués and Modolell, 2010)

sc^A is a suppressor of scutellar bristle | increased number phenotype of Scer\GAL4^pnr-MD237, tup^RNAi.UAS

(de Navascués and Modolell, 2010)

Additional Comments

Genetic Interactions

Statement

Reference

Overexpression of tup^{dsRNA.Scer\UAS} under the control of Scer\GAL4^pnr-MD237 in a sc^A mutant background does not lead to the formation of supernumerary scutellar bristles.

No significant increase in the number of scutellar bristles above the sc^A background is observed when tup^ex4 clones are induced in a sc^A mutant background.

(de Navascués and Modolell, 2010)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

I.J. Agol

(Agol, 1936)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

sc^A

(de Navascués and Modolell, 2010, Mari-Beffa et al., 1991)

Name Synonyms

of Agol

Secondary FlyBase IDs

References (6)

Report Sections

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