FB2024_03 , released June 25, 2024
Allele: Dmel\Dhc64C77
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General Information
Symbol
Dmel\Dhc64C77
Species
D. melanogaster
Name
FlyBase ID
FBal0016299
Feature type
allele
Associated gene
Dmel\Dhc64C
Associated Insertion(s)
Carried in Construct
Also Known As
Su(Gl)77
Key Links
Allele class
Mutagen
Nature of the Allele
Allele class
Mutagen
ethyl methanesulfonate
(Harte and Kankel, 1982)
Progenitor genotype
Cytology
Description
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressor of
      Statement
      Reference

      Dhc64C8-1/Dhc64C77 is a suppressor of visible | dominant phenotype of DCTN1-p150Gl-1

      (Iyadurai et al., 2008)
      NOT Suppressor of
      Statement
      Reference

      Dhc64C77/Su(Gl)77[+] is a non-suppressor of visible | dominant phenotype of DCTN1-p150Gl-1, S[+]/S1

      (Iyadurai et al., 2008)

      Dhc64C8-1/Dhc64C77 is a non-suppressor of visible | dominant phenotype of DCTN1-p150Gl-1, S[+]/S1

      (Iyadurai et al., 2008)
      Phenotype Manifest In
      Suppressor of
      Statement
      Reference

      Dhc64C8-1/Dhc64C77 is a suppressor of eye phenotype of DCTN1-p150Gl-1

      (Iyadurai et al., 2008)
      NOT Suppressor of
      Statement
      Reference

      Dhc64C77/Su(Gl)77[+] is a non-suppressor of eye phenotype of DCTN1-p150Gl-1, S[+]/S1

      (Iyadurai et al., 2008)

      Dhc64C8-1/Dhc64C77 is a non-suppressor of eye phenotype of DCTN1-p150Gl-1, S[+]/S1

      (Iyadurai et al., 2008)
      Additional Comments
      Genetic Interactions
      Statement
      Reference

      The S1 mutation overcomes the suppression of the Gl1 rough eye phenotype by Dhc64C77, so that triple heterozygotes have an enhanced rough eye phenotype compared to Gl1 single heterozygotes.

      Gl1 Dhc64C77 Dhc64C8-1 flies have completely wild-type eyes.

      The enhanced rough eye phenotype of Gl1/+ S1/+ flies is not suppressed by Dhc64C77/Dhc64C8-1.

      (Iyadurai et al., 2008)
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Comments

      "Su(Gl)77" corresponds to an allele of Dhc64C; females carrying "Su(Gl)77" in combination with a deficiency that removes Dhc64C are sterile, but this sterile phenotype is completely rescued by introduction of a transgene containing Dhc64C.

      (Iyadurai et al., 2008)

      Allelism not established, independent mutations with suppressing effects on Gl, map between ru and h and are presumed to be allelic.

      (Lindsley and Zimm, 1992)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (3)
      Reported As
      Symbol Synonym
      Dhc64C77
      Su(Gl)77
      (Iyadurai et al., 2008, Harte and Kankel, 1982)
      Su(Gl)771
      (Lindsley and Zimm, 1992)
      Name Synonyms
      Secondary FlyBase IDs
        References (3)