Mutation is within the 4th EGF-like repeat in the Dl extracellular domain.
Amino acid replacement: G305R.
G19306417A
G305R | Dl-PA; G305R | Dl-PB; G305R | Dl-PC
G305R
Lethal when hemizygous. Homozygotes have a recessive wing phenotype: delta-like swellings at distal tips of wing veins.
Selected as: Modifier of Notch "split" alleles.