103bp deletion (nucleotides 2244 to 2346) within the region encoding the extracellular C-terminal domain. This produces a frameshift that results in the C-terminal 234 amino acids being replaced with an unrelated amino acid sequence.
Deletion of the most distal portion of the extracellular domain.
Nrt1 is a 103 base pair deletion, resulting in a frameshift.
Defects in the axon patterning within the embryonic CNS. Synergistic phenotypes are observed in double mutants with Nrg.
Nrt1 has axon | embryonic stage phenotype, enhanceable by Nrgl4
Nrt1 has axon | embryonic stage phenotype, enhanceable by Nrgl7