FlyBase Allele Report: Dmel\r[hd1]

General Information

Symbol

Dmel\r^hd1

Species

D. melanogaster

Name

FlyBase ID

FBal0032541

Feature type

allele

Associated gene

Dmel\r

Associated Insertion(s)

P{}r^hd1

Carried in Construct

Key Links

Allele class

hypomorphic allele - genetic evidence

Mutagen

PM hybrid dysgenesis

Nature of the Allele

Allele class

hypomorphic allele - genetic evidence

(Roykhman et al., 2007, Wojcik et al., 1994, Tsubota and Schedl, 1986)

Mutagen

PM hybrid dysgenesis

(Zerges et al., 1992, Tsubota and Schedl, 1986)

Progenitor genotype

Associated Insertion(s)

P{}r^hd1

Cytology

Description

P element insertion into 1st exon of r, approximately 60bp upstream the 5' splice junction of exon 1.

(Zerges et al., 1992)

1.1kb insertion into the 5' non-coding region.

(Tsubota and Schedl, 1986)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

female sterile | recessive

(Begley et al., 1995)

visible | recessive

(Begley et al., 1995, Zerges et al., 1992, Tsubota and Schedl, 1986)

Phenotype Manifest In

posterior wing margin

(Roykhman et al., 2007)

wing

(Roykhman et al., 2007, Begley et al., 1995, Wojcik et al., 1994, Tsubota and Schedl, 1986)

wing margin bristle

(Roykhman et al., 2007)

Detailed Description

Statement

Reference

The wings of r^hd1 mutants are nearly wild-type in appearance. Characteristically, the posterior wing margin exhibits a disorderly array of bristles.

(Roykhman et al., 2007)

Wings truncated. Female sterile.

(Begley et al., 1995)

Homozygotes display a slightly truncated wing.

(Wojcik et al., 1994)

Moderate r wing phenotype.

(Zerges et al., 1992)

Moderate rudimentary wing phenotype. Rank 2-3 phenotype according to system of Green, (FBrf0015303).

(Tsubota and Schedl, 1986)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

NOT suppressed by

Statement

Reference

r^hd1 has female sterile phenotype, non-suppressible by Vsp37A^p1

(Begley et al., 1995)

Phenotype Manifest In

Enhanced by

Statement

Reference

r^hd1 has wing phenotype, enhanceable by e(r)^14-1

(Roykhman et al., 2007)

r^hd1 has wing margin bristle phenotype, enhanceable by e(r)^27-1

(Roykhman et al., 2007)

r^hd1 has wing phenotype, enhanceable by e(r)^27-1

(Roykhman et al., 2007)

r^hd1 has wing margin bristle phenotype, enhanceable by e(r)^27-8

(Roykhman et al., 2007)

r^hd1 has wing phenotype, enhanceable by e(r)^27-8

(Roykhman et al., 2007)

r^hd1 has wing margin bristle phenotype, enhanceable by e(r)^35-5

(Roykhman et al., 2007)

r^hd1 has wing phenotype, enhanceable by e(r)^35-5

(Roykhman et al., 2007)

r^hd1 has wing margin bristle phenotype, enhanceable by e(r)^37-6

(Roykhman et al., 2007)

r^hd1 has wing phenotype, enhanceable by e(r)^37-6

(Roykhman et al., 2007)

r^hd1 has wing margin bristle phenotype, enhanceable by e(r)^39-2

(Roykhman et al., 2007)

r^hd1 has wing phenotype, enhanceable by e(r)^39-2

(Roykhman et al., 2007)

r^hd1 has wing margin bristle phenotype, enhanceable by e(r)^41-2

(Roykhman et al., 2007)

r^hd1 has wing phenotype, enhanceable by e(r)^41-2

(Roykhman et al., 2007)

r^hd1 has wing phenotype, enhanceable by e(r)^p1

(Wojcik et al., 1994)

NOT Enhanced by

Statement

Reference

r^hd1 has posterior wing margin phenotype, non-enhanceable by e(r)^18-2

(Roykhman et al., 2007)

r^hd1 has posterior wing margin phenotype, non-enhanceable by e(r)^51-16

(Roykhman et al., 2007)

r^hd1 has wing margin bristle phenotype, non-enhanceable by e(r)^51-16

(Roykhman et al., 2007)

r^hd1 has wing phenotype, non-enhanceable by e(r)^51-16

(Roykhman et al., 2007)

r^hd1 has posterior wing margin phenotype, non-enhanceable by e(r)^53-4

(Roykhman et al., 2007)

r^hd1 has wing margin bristle phenotype, non-enhanceable by e(r)^53-4

(Roykhman et al., 2007)

r^hd1 has wing phenotype, non-enhanceable by e(r)^53-4

(Roykhman et al., 2007)

r^hd1 has wing margin bristle phenotype, non-enhanceable by e(r)^18-2

(Roykhman et al., 2007)

r^hd1 has posterior wing margin phenotype, non-enhanceable by rdgA^KG01830

(Roykhman et al., 2007)

r^hd1 has wing phenotype, non-enhanceable by e(r)^18-2

(Roykhman et al., 2007)

r^hd1 has wing margin bristle phenotype, non-enhanceable by rdgA^KG01830

(Roykhman et al., 2007)

r^hd1 has wing phenotype, non-enhanceable by rdgA^KG01830

(Roykhman et al., 2007)

r^hd1 has posterior wing margin phenotype, non-enhanceable by e(r)^47-1

(Roykhman et al., 2007)

r^hd1 has wing margin bristle phenotype, non-enhanceable by e(r)^47-1

(Roykhman et al., 2007)

r^hd1 has wing phenotype, non-enhanceable by e(r)^47-1

(Roykhman et al., 2007)

r^hd1 has posterior wing margin phenotype, non-enhanceable by e(r)^48-2

(Roykhman et al., 2007)

r^hd1 has wing margin bristle phenotype, non-enhanceable by e(r)^48-2

(Roykhman et al., 2007)

r^hd1 has wing phenotype, non-enhanceable by e(r)^48-2

(Roykhman et al., 2007)

Suppressed by

Statement

Reference

r^hd1 has wing phenotype, suppressible by Vsp37A^p1

(Begley et al., 1995)

Additional Comments

Genetic Interactions

Statement

Reference

CG15352^KG01830 does not exhibit a noticeable effect on the r^hd1 phenotype.

The mutants e(r)^18-2, e(r)^47-1, e(r)^48-2, e(r)^51-16 and e(r)^53-4 do not enhance the r^hd1 mutant wing phenotype.

e(r)^14-1 mutants display a very slight enhancement of the r^hd1 phenotype. The wings are slightly more truncated than those of r^hd1 mutants.

The presence of a e(r)^27-1 mutant background noticeably enhances the r^hd1 wing phenotype.

The presence of a e(r)^27-8 mutant background noticeably enhances the r^hd1 wing phenotype.

The presence of a e(r)^35-5 mutant background noticeably enhances the r^hd1 wing phenotype.

The presence of a e(r)^37-6 mutant background noticeably enhances the r^hd1 wing phenotype.

The presence of a e(r)^39-2 mutant background noticeably enhances the r^hd1 wing phenotype.

The presence of a e(r)^41-2 mutant background noticeably enhances the r^hd1 wing phenotype.

(Roykhman et al., 2007)

Wing truncation phenotype, but not sterility, is suppressed by mod(r)^p1.

(Begley et al., 1995)

Wing truncation seen in homozygotes is more severe in the presence of e(r)^p1.

(Wojcik et al., 1994)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

Comments

The inserts in r^hd1, r^hd2, r^hd3 and r^hd5 all lie within the same 1.4kb EcoRI fragment.

(Tsubota and Schedl, 1986)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (1)

Reported As

Symbol Synonym

r^hd1

(Roykhman et al., 2007)

Name Synonyms

Secondary FlyBase IDs

References (6)

Report Sections

Open Close