FB2024_03 , released June 25, 2024
Allele: Dmel\Abd-BM3
Open Close
General Information
Symbol
Dmel\Abd-BM3
Species
D. melanogaster
Name
FlyBase ID
FBal0033316
Feature type
allele
Associated gene
Dmel\Abd-B
Associated Insertion(s)
Carried in Construct
Key Links
Allele class

loss of function allele

Mutagen
Nature of the Allele
Allele class

loss of function allele

(Celniker et al., 1990, de Lorenzi and Bienz, 1990)
Mutagen
ethyl methanesulfonate
(Kuhn et al., 1993, Kuhn et al., 1992, de Lorenzi and Bienz, 1990, Sanchez-Herrero et al., 1985)
Progenitor genotype
Cytology
Description

Mutations within coding region: eliminate m function.

(de Lorenzi and Bienz, 1990)
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Abd-BM3 male mutant clones exhibit transformation of the tiny A8 segment into an anterior abdominal segment.

      (Foronda et al., 2006)

      Adult females have eight abdominal segments, lack genitalia and (occasionally) analia. Males have eight abdominal segments and retain both genitalia and analia. In these flies parasegment 13 is transformed towards 10 while parasegment 14 is unaffected. Embryos lack posterior spiracles.

      (Kuhn et al., 1995)

      Reduced penetrance of head defect phenotype when in trans with Abd-Biab9-tuh-3.

      (Kuhn et al., 1993)

      A5-A8 are transformed to A4, females lack genitalia, and there is a weak haploinsufficient transformation of A5-A8. Parasegments 10-13 are transformed to parasegment 9 in embryos.

      (Sanchez-Herrero and Crosby, 1988)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      Comments
      Comments

      Mutant in m function. This allele originally described in Sanchez-Herrero et al, Nature 313: 108--113.

      (Kuhn et al., 1992)

      m- r+ mutant, eliminating function of Abd-B function.

      (Kuhn et al., 1993)

      Abd-B m-r+ mutation.

      (Kuhn et al., 1995)
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      Abd-BM3
      Abd-Bm3
      (de Lorenzi and Bienz, 1990)
      Name Synonyms
      Secondary FlyBase IDs
        References (9)