FlyBase Allele Report: Dmel\Abd-B[iab8-D16]

General Information

Symbol

Dmel\Abd-B^iab8-D16

Species

D. melanogaster

Name

FlyBase ID

FBal0000110

Feature type

allele

Associated gene

Dmel\Abd-B

Associated Insertion(s)

Carried in Construct

Also Known As

Abd-B^D16

Key Links

Allele class

loss of function allele

amorphic allele - genetic evidence

Mutagen

ethyl methanesulfonate

Nature of the Allele

Allele class

amorphic allele - genetic evidence

(Celniker et al., 1990)

loss of function allele

(Mack et al., 1997, Boulet et al., 1991, Karch et al., 1990)

Mutagen

ethyl methanesulfonate

(Kuhn et al., 1993, Karch et al., 1985)

Progenitor genotype

Cytology

Polytene chromosomes normal.

(Hendrickson and Sakonju, 1995)

Description

Deletion removes the entire iab-8 and iab-9 region of Abd-B.

(Celniker et al., 1990)

Point mutation.

(Karch et al., 1985)

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

No Abd-B protein was detected in embryos.

(Boulet et al., 1991)

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

abnormal body color | somatic clone (with Df(3R)P9)

(Hendrickson and Sakonju, 1995)

female sterile | dominant

(Karch et al., 1985)

lethal (with Df(3R)P9)

(Hendrickson and Sakonju, 1995)

lethal | homeotic

(Sanchez-Herrero and Crosby, 1988)

lethal | recessive

(Kuhn et al., 1995, Karch et al., 1985)

male sterile | dominant

(Karch et al., 1985)

visible

(Sipos et al., 1998)

visible | homeotic | somatic clone

(Sanchez-Herrero and Crosby, 1988)

Phenotype Manifest In

abdominal segment 4 | ectopic | somatic clone

(Sanchez-Herrero and Crosby, 1988)

abdominal segment 5 | somatic clone

(Sanchez-Herrero and Crosby, 1988)

abdominal segment 6 | somatic clone

(Sanchez-Herrero and Crosby, 1988)

abdominal segment 7 | somatic clone

(Sanchez-Herrero and Crosby, 1988)

abdominal segment 8 | somatic clone

(Sanchez-Herrero and Crosby, 1988)

abdominal tergite 7 | male

(Sipos et al., 1998)

adult abdomen | somatic clone (with Df(3R)P9)

(Hendrickson and Sakonju, 1995)

denticle & embryonic abdominal segment 9 | somatic clone

(Sanchez-Herrero and Crosby, 1988)

denticle | somatic clone

(Sanchez-Herrero and Crosby, 1988)

embryonic/larval posterior spiracle | embryonic stage

(Kuhn et al., 1995)

embryonic abdominal segment 8 | somatic clone

(Sanchez-Herrero and Crosby, 1988)

embryonic abdominal segment 9 | somatic clone

(Sanchez-Herrero and Crosby, 1988)

genitalia

(Kuhn et al., 1993)

genitalia | female | somatic clone

(Sanchez-Herrero and Crosby, 1988)

parasegment 9 | ectopic | somatic clone

(Sanchez-Herrero and Crosby, 1988)

parasegment 10 | somatic clone

(Sanchez-Herrero and Crosby, 1988)

parasegment 11 | somatic clone

(Sanchez-Herrero and Crosby, 1988)

parasegment 12 | somatic clone

(Sanchez-Herrero and Crosby, 1988)

parasegment 13 | somatic clone

(Sanchez-Herrero and Crosby, 1988)

sclerite & abdominal segment 8 & embryo | somatic clone

(Sanchez-Herrero and Crosby, 1988)

sclerite | somatic clone

(Sanchez-Herrero and Crosby, 1988)

Detailed Description

Statement

Reference

Abd-B^iab8-D16/Abd-B^Fab7-1 males show a reduction in size of the seventh abdominal tergite to the size of the seventh abdominal tergite in Abd-B^Sz/+ males, however, the sixth abdominal tergite is larger in Abd-B^iab8-D16/Abd-B^Fab7-1 males than in Abd-B^Sz/+ males and more closely resembles wild-type.

(Sipos et al., 1998)

The Abd-B^iab8-D16/Df(3R)P9 combination is lethal, and clones of Abd-B^iab8-D16/Df(3R)P9 show no male specific pigment in abdominal segments.

(Hendrickson and Sakonju, 1995)

Homozygotes die as late embryos or early first instar larvae. Embryos have no posterior spiracles.

(Kuhn et al., 1995)

Heterozygotes with Abd-B^iab9-tuh-3 exhibit genital defects.

(Kuhn et al., 1993)

A5-A8 (including female genitalia) transformed to A4 in mosaics. Embryos have sclerotic plates in pA8 and occasional extra denticles in A9, and parasegments 10-13 are transformed to parasegment 9.

(Sanchez-Herrero and Crosby, 1988)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Suppressed by

Statement

Reference

Df(3R)P9/Abd-B^iab8-D16 has lethal phenotype, suppressible by Dp(3;Y)JX3

(Hendrickson and Sakonju, 1995)

Other

Statement

Reference

Df(3R)P9/Abd-B^iab8-D16, Dp(3;Y)JX3 has viable phenotype

(Hendrickson and Sakonju, 1995)

Df(3R)P9/Abd-B^iab8-D16, Dp(3;Y)JX3 has visible | somatic clone phenotype

(Hendrickson and Sakonju, 1995)

Phenotype Manifest In

Other

Statement

Reference

Abd-B^iab8-D16/Abd-B^iab9-tuh-3, tuh1^g has male genitalia phenotype

(Mack et al., 1997)

Df(3R)P9/Abd-B^iab8-D16, Dp(3;Y)JX3 has abdominal segment 6 | somatic clone phenotype

(Hendrickson and Sakonju, 1995)

Df(3R)P9/Abd-B^iab8-D16, Dp(3;Y)JX3 has abdominal segment 7 | somatic clone phenotype

(Hendrickson and Sakonju, 1995)

Abd-B^iab8-D16, Scr^hs.PZ has parasegment 1 phenotype

(Andrew et al., 1994)

Abd-B^iab8-D16, Scr^hs.PZ has embryonic/larval salivary gland | embryonic stage phenotype

(Andrew et al., 1994)

Abd-B^iab8-D16, Scr^hs.PZ has mandibular segment phenotype

(Andrew et al., 1994)

Abd-B^iab8-D16, Scr^hs.PZ has parasegment 14 phenotype

(Andrew et al., 1994)

Additional Comments

Genetic Interactions

Statement

Reference

Mutant phenotype of Abd-B^iab9-tuh-3/Abd-B^iab8-D16 responds to tuh1^g maternal effect by producing genital defects.

(Mack et al., 1997)

Dp(3;Y)JX3; Abd-B^iab8-D16/Df(3R)P9 flies are fully viable and show male specific pigment in A6 and A7.

(Hendrickson and Sakonju, 1995)

In the presence of construct P{HS-Scr.Z} ectopic salivary glands form in parasegments 0, 1 and 14.

(Andrew et al., 1994)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Fails to complement

Abd-B^Sz

(Sipos et al., 1998)

Abd-B^Uab-1

(Sanchez-Herrero and Crosby, 1988)

Abd-B^iab9-x23-1

(Sanchez-Herrero and Crosby, 1988)

Abd-B^iab9-tuh-3

(Sanchez-Herrero and Crosby, 1988)

Abd-B^iab9-Tab

(Sanchez-Herrero and Crosby, 1988)

Abd-B^iab8-D15

(Sanchez-Herrero and Crosby, 1988)

Abd-B^iab8-D14

(Sanchez-Herrero and Crosby, 1988)

Abd-B^iab8-D6

(Sanchez-Herrero and Crosby, 1988)

Abd-B^iab8-rv82

(Sanchez-Herrero and Crosby, 1988)

Abd-B^iab8-rv96

(Sanchez-Herrero and Crosby, 1988)

Abd-B^iab8-rv111

(Sanchez-Herrero and Crosby, 1988)

Abd-B^iab8-rv185

(Sanchez-Herrero and Crosby, 1988)

Abd-B^iab8-rv100

(Sanchez-Herrero and Crosby, 1988)

Abd-B^iab8-rv114

(Sanchez-Herrero and Crosby, 1988)

Abd-B^iab8-rv89

(Sanchez-Herrero and Crosby, 1988)

Abd-B^iab8-rv175

(Sanchez-Herrero and Crosby, 1988)

Abd-B^iab8-rv107

(Sanchez-Herrero and Crosby, 1988)

Abd-B^M9

(Sanchez-Herrero and Crosby, 1988)

Abd-B^M7

(Sanchez-Herrero and Crosby, 1988)

Abd-B^M4

(Sanchez-Herrero and Crosby, 1988)

Abd-B^M2

(Sanchez-Herrero and Crosby, 1988)

Abd-B³⁸⁰

(Sanchez-Herrero and Crosby, 1988)

Abd-B^S2

(Sanchez-Herrero and Crosby, 1988)

Abd-B^S1

(Sanchez-Herrero and Crosby, 1988)

Abd-B^M6

(Sanchez-Herrero and Crosby, 1988)

Abd-B^M5

(Sanchez-Herrero and Crosby, 1988)

Abd-B^M3

(Sanchez-Herrero and Crosby, 1988)

Abd-B^S9

(Sanchez-Herrero and Crosby, 1988)

Abd-B^S8

(Sanchez-Herrero and Crosby, 1988)

Abd-B^S5

(Sanchez-Herrero and Crosby, 1988)

Abd-B^R

(Sanchez-Herrero and Crosby, 1988)

Abd-B^F

(Sanchez-Herrero and Crosby, 1988)

Comments

Abd-B^iab8-D16 does not complement the iab-7 loss of function mutant Abd-B^Sz in segment A7 in males.

(Sipos et al., 1998)

Fails to complement all mutations in the Abd-B domain.

(Sanchez-Herrero and Crosby, 1988)

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

Duncan.

Comments

Strong allele.

(Celniker and Lewis, 1987)

Fails to complement all mutations in the Abd-B domain.

(Sanchez-Herrero and Crosby, 1988)

Embryos lack Abd-B protein, this correlates with the loss of both the m and r genetic functions.

(Boulet et al., 1991)

m^- r^- Abd-B mutation.

(Kuhn et al., 1993)

Genetically null for the Abd-B m function.

(Hendrickson and Sakonju, 1995)

Abd-B m^-r^- mutation.

(Kuhn et al., 1995)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (5)

Reported As

Symbol Synonym

Abd-B^D16

(Maeda et al., 2018, Moris-Sanz et al., 2015, Gummalla et al., 2012, Chen et al., 2005, Sipos et al., 1998, Mack et al., 1997, Cimbora and Sakonju, 1995, Hendrickson and Sakonju, 1995, Andrew et al., 1994, Kuhn et al., 1993, Celniker and Lewis, 1987)

Abd-B^iab8-D16

iab-7^D16

(Sanchez-Herrero and Crosby, 1988)

iab7^D16

iab8^D16

(Celniker and Lewis, 1987)

Name Synonyms

Secondary FlyBase IDs

References (17)

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