FB2024_03 , released June 25, 2024
Allele: Dmel\tuh1g
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General Information
Symbol
Dmel\tuh1g
Species
D. melanogaster
Name
genital defects
FlyBase ID
FBal0035877
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Also Known As
tuh-1g
Key Links
Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Progenitor genotype
    Cytology
    Description
    Mutations Mapped to the Genome
    Curation Data
    Type
    Location
    Additional Notes
    References
    Variant Molecular Consequences
    Associated Sequence Data
    DNA sequence
    Protein sequence
     
    Expression Data
    Reporter Expression
    Additional Information
    Statement
    Reference
     
    Marker for
    Reflects expression of
    Reporter construct used in assay
    Human Disease Associations
    Disease Ontology (DO) Annotations
    Models Based on Experimental Evidence ( 0 )
    Disease
    Evidence
    References
    Modifiers Based on Experimental Evidence ( 0 )
    Disease
    Interaction
    References
    Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
     
    Disease-implicated variant(s)
     
    Phenotypic Data
    Phenotypic Class
    Phenotype Manifest In
    Detailed Description
    Statement
    Reference

    Females homozygous for tuh1h produce adult offspring with significantly more bristles than homozygous tuh1g or tuh1g/tuh1h females. Increased bristle number occurs in the head, thorax and anterior and posterior abdomen. tuh1h is completely recessive to tuh1g. The phenotype is temperature sensitive, with the difference in bristle number between the offspring of tuh1h and tuh1g homozygous females being greatest at 18oC. Flies homozygous for tuh1h develop significantly faster than flies heterozygous or homozygous for tuh1g at 18oC, although there is no significant difference in developmental time at 25oC.

    External Data
    Interactions
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    Phenotypic Class
    Other
    Phenotype Manifest In
    Additional Comments
    Genetic Interactions
    Statement
    Reference

    Maternal effect gene. Abd-Biab9-tuh-3 acts as a recessive allele in combination with tuh1g, causing internal and external genitalia to be deleted.

    Xenogenetic Interactions
    Statement
    Reference
    Complementation and Rescue Data
    Comments
    Images (0)
    Mutant
    Wild-type
    Stocks (0)
    Notes on Origin
    Discoverer
    External Crossreferences and Linkouts ( 0 )
    Synonyms and Secondary IDs (6)
    Reported As
    Name Synonyms
    genital defects
    Secondary FlyBase IDs
      References (7)