FlyBase Allele Report: Ecol\lacZ[dpp.PB]

General Information

Symbol

Ecol\lacZ^dpp.PB

Species

E. coli

Name

FlyBase ID

FBal0041161

Feature type

allele

Associated gene

Ecol\lacZ

Associated Insertion(s)

Carried in Construct

P{dpp-lacZ.B}

Transgenic product class

Mutagen

in vitro construct

Nature of the Allele

Transgenic product class

Mutagen

in vitro construct

(Basler and Struhl, 1994, Diaz-Benjumea et al., 1994)

Progenitor genotype

Carried in construct

P{dpp-lacZ.B}

Cytology

Description

lacZ gene expression is driven by a dpp promoter.

(Basler and Struhl, 1994, Diaz-Benjumea et al., 1994)

Allele components

Component

Use(s)

Encoded product / tool

lacZ

reporter enzyme

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

distribution deduced from reporter

Stage

Tissue/Position (including subcellular localization)

Reference

larval stage

anterior-posterior compartment boundary of the leg disc | dorsal

(Diaz-Benjumea et al., 1994)

anterior-posterior compartment boundary of the antennal disc | dorsal

(Diaz-Benjumea et al., 1994)

leg disc | anterior

(Diaz-Benjumea et al., 1994)

antennal disc | anterior

(Diaz-Benjumea et al., 1994)

third instar larval stage

eye disc anterior to the morphogenetic furrow

(Wiersdorff et al., 1996)

eye disc | lateral | restricted

(Wiersdorff et al., 1996)

anterior-posterior compartment boundary of the leg disc

(Basler and Struhl, 1994)

anterior-posterior compartment boundary of the wing disc

(Casali and Struhl, 2004, Chamoun et al., 2001, Basler and Struhl, 1994)

Additional Information

Statement

Reference

Expression is observed in a broad strip about 15-20 cell diameters, with a sharp peak at the anterior/posterior compartment boundary and declining anteriorly with distance from the posterior compartment.

(Casali and Struhl, 2004)

Early third instar expression is observed at the lateral margins of the eye disc until the morphogenetic furrow has passed. Expression in the mid to late third instar eye disc is observed to be anterior to the morphogenetic furrow.

(Wiersdorff et al., 1996)

Expression is observed anterior to hh expression at the anterior/posterior boundary of the wing and leg discs.

(Basler and Struhl, 1994)

Expression in leg discs is observed in a band of cells anterior to the anterior/posterior boundary.

(Diaz-Benjumea et al., 1994)

Marker for

anterior-posterior compartment boundary of the wing disc

(Casali and Struhl, 2004, Chamoun et al., 2001, Wiersdorff et al., 1996, Basler and Struhl, 1994, Diaz-Benjumea et al., 1994)

Reflects expression of

dpp

(Casali and Struhl, 2004, Chamoun et al., 2001, Wiersdorff et al., 1996, Basler and Struhl, 1994, Diaz-Benjumea et al., 1994)

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

Phenotype Manifest In

Detailed Description

Statement

Reference

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Additional Comments

Genetic Interactions

Statement

Reference

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (0)

Notes on Origin

Discoverer

Blackman

(Basler and Struhl, 1994, Diaz-Benjumea et al., 1994)

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

Ecol\lacZ^dpp.PB

lacZ^dpp.PB

Name Synonyms

Secondary FlyBase IDs

References (7)

Report Sections

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