FB2024_03 , released June 25, 2024
Allele: Dmel\RfC4B6
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General Information
Symbol
Dmel\RfC4B6
Species
D. melanogaster
Name
FlyBase ID
FBal0045036
Feature type
allele
Associated gene
Dmel\RfC4
Associated Insertion(s)
Carried in Construct
Key Links
Allele class
Mutagen
    Nature of the Allele
    Allele class
    Mutagen
    Progenitor genotype
    Cytology
    Description
    Mutations Mapped to the Genome
    Curation Data
    Type
    Location
    Additional Notes
    References
    Variant Molecular Consequences
    Associated Sequence Data
    DDBJ / EMBL / GenBank
    DNA sequence
    Protein sequence
     
    UniProtKB/Swiss-Prot
      UniProtKB/TrEMBL
        Expression Data
        Reporter Expression
        Additional Information
        Statement
        Reference
         
        Marker for
        Reflects expression of
        Reporter construct used in assay
        Human Disease Associations
        Disease Ontology (DO) Annotations
        Models Based on Experimental Evidence ( 0 )
        Disease
        Evidence
        References
        Modifiers Based on Experimental Evidence ( 0 )
        Disease
        Interaction
        References
        Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
         
        Disease-implicated variant(s)
         
        Phenotypic Data
        Phenotypic Class
        Phenotype Manifest In
        Detailed Description
        Statement
        Reference

        Heterozygotes have wild-type eyes.

        (Jaffe and Jongens, 2001)

        Homozygous larvae have no imaginal discs, suggesting a defect in imaginal disc proliferation.

        (Harrison et al., 1995)
        External Data
        Interactions
        Show genetic interaction network for Enhancers & Suppressors
        Phenotypic Class
        Phenotype Manifest In
        Enhancer of
        Statement
        Reference

        RfC40[+]/RfC4B6 is an enhancer of ommatidium phenotype of cutletrJ865a

        (Jaffe and Jongens, 2001)

        RfC40[+]/RfC4B6 is an enhancer of eye photoreceptor cell phenotype of cutletrJ865a

        (Jaffe and Jongens, 2001)
        Additional Comments
        Genetic Interactions
        Statement
        Reference

        The cutletrJ865a eye phenotype is enhanced by one copy of RfC40B6; the majority of ommatidial clusters in these flies have an abnormal number of photoreceptor cells and a large number of ommatidia are fused.

        (Jaffe and Jongens, 2001)
        Xenogenetic Interactions
        Statement
        Reference
        Complementation and Rescue Data
        Comments
        Images (0)
        Mutant
        Wild-type
        Stocks (1)
        Notes on Origin
        Discoverer
        External Crossreferences and Linkouts ( 0 )
        Synonyms and Secondary IDs (5)
        Reported As
        Symbol Synonym
        RfC40B6
        (Christensen et al., 2009.2.28, Christensen et al., 2009.2.28)
        RfC4B6
        l(3)64AiB6
        (Harrison et al., 1995)
        l(3)rfc40B6
        (Jaffe and Jongens, 2001)
        rfc40B6
        (Harrison, 1999.5.12)
        Name Synonyms
        Secondary FlyBase IDs
          References (5)