FlyBase Allele Report: Dmel\cv-2[225-3]

General Information

Symbol

Dmel\cv-2^225-3

Species

D. melanogaster

Name

FlyBase ID

FBal0045481

Feature type

allele

Associated gene

Dmel\cv-2

Associated Insertion(s)

P{lacW}cv-2^225-3

Carried in Construct

Key Links

Allele class

Mutagen

P-element activity

Nature of the Allele

Allele class

Mutagen

P-element activity

(Conley and Blair, 1996)

Progenitor genotype

Associated Insertion(s)

P{lacW}cv-2^225-3

Cytology

Description

P{lacW} insertion upstream of cv-2.

(Conley et al., 2000)

Allele components

Component

Use(s)

Inserted element

P{lacW}

enhancer trap

Encoded product / tool

lacZ

reporter enzyme

Tagged with

Tag:NLS(P)

nuclear protein localization tag

Mutations Mapped to the Genome

Curation Data

Type

Location

Additional Notes

References

Variant Molecular Consequences

Associated Sequence Data

DDBJ / EMBL / GenBank

DNA sequence

Protein sequence

UniProtKB/Swiss-Prot

UniProtKB/TrEMBL

Expression Data

Reporter Expression

Additional Information

Statement

Reference

Marker for

Reflects expression of

Reporter construct used in assay

Human Disease Associations

Disease Ontology (DO) Annotations

Models Based on Experimental Evidence ( 0 )

Disease

Evidence

References

Modifiers Based on Experimental Evidence ( 0 )

Disease

Interaction

References

Comments on Models/Modifiers Based on Experimental Evidence ( 0 )

Disease-implicated variant(s)

Phenotypic Data

Phenotypic Class

visible | dominant

(Dworkin and Gibson, 2006)

Phenotype Manifest In

posterior crossvein

(Dworkin and Gibson, 2006, Conley et al., 2000)

wing | posterior

(Dworkin and Gibson, 2006)

Detailed Description

Statement

Reference

Homozygotes/hemizygotes are posterior crossveinless.

Heterozygotes show a direct effect on the shape of the wing, having a significant effect in the posterior region (mostly shifting the position of the posterior crossvein relative to wild type), but no effect in the anterior region.

(Dworkin and Gibson, 2006)

Homozygotes lack typically lack most or all of the posterior crossvein.

(Conley et al., 2000)

External Data

Linkouts

Interactions

Show genetic interaction network for Enhancers & Suppressors

Phenotypic Class

Phenotype Manifest In

Enhanced by

Statement

Reference

cv-2^k03511/cv-2^225-3 has posterior crossvein phenotype, enhanceable by gbb⁴

(Conley et al., 2000)

Additional Comments

Genetic Interactions

Statement

Reference

The addition of gbb⁴ to cv-2^225-3/cv-2^k03511 animals produces an enhancement of the posterior crossvein phenotype seen in these flies.

(Conley et al., 2000)

Xenogenetic Interactions

Statement

Reference

Complementation and Rescue Data

Comments

Images (0)

Mutant

Wild-type

Stocks (1)

Bloomington

6342

y¹ w^*; P{lacW}cv-2^225-3

Notes on Origin

Discoverer

External Crossreferences and Linkouts ( 0 )

Synonyms and Secondary IDs (2)

Reported As

Symbol Synonym

225-3

(Dworkin and Gibson, 2006)

cv-2^225-3

Name Synonyms

Secondary FlyBase IDs

References (6)

Report Sections

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