FB2024_03 , released June 25, 2024
Allele: Dmel\ftzhb.PP
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General Information
Symbol
Dmel\ftzhb.PP
Species
D. melanogaster
Name
hunchback promoter construct of Parkhurst
FlyBase ID
FBal0045741
Feature type
allele
Associated gene
Dmel\ftz
Associated Insertion(s)
Carried in Construct
P{hb-ftz}
Key Links
Transgenic product class
genomic_DNA
(Parkhurst and Ish-Horowicz, 1991)
wild_type
(Parkhurst and Ish-Horowicz, 1991)
Mutagen
Nature of the Allele
Transgenic product class
genomic_DNA
(Parkhurst and Ish-Horowicz, 1991)
wild_type
(Parkhurst and Ish-Horowicz, 1991)
Mutagen
in vitro construct
(Parkhurst and Ish-Horowicz, 1991)
Progenitor genotype
Carried in construct
P{hb-ftz}
Cytology
Description

Contains ftz genomic DNA sequence from -75bp through to +2.5kb, under the control of the hb promoter.

(Parkhurst and Ish-Horowicz, 1991)
Allele components
Component
Use(s)
Regulatory region(s)
hb
Encoded product / tool
ftz
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DDBJ / EMBL / GenBank
DNA sequence
Protein sequence
 
UniProtKB/Swiss-Prot
    UniProtKB/TrEMBL
      Expression Data
      Reporter Expression
      Additional Information
      Statement
      Reference
       
      Marker for
      Reflects expression of
      Reporter construct used in assay
      Human Disease Associations
      Disease Ontology (DO) Annotations
      Models Based on Experimental Evidence ( 0 )
      Disease
      Evidence
      References
      Modifiers Based on Experimental Evidence ( 0 )
      Disease
      Interaction
      References
      Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
       
      Disease-implicated variant(s)
       
      Phenotypic Data
      Phenotypic Class
      Phenotype Manifest In
      Detailed Description
      Statement
      Reference

      Approximately 20% of ftzhb.PP homozygous adults lack external genitalia that derive from anlagen of segments A8 to A11.

      (Parkhurst and Ish-Horowicz, 1991)
      External Data
      Interactions
      Show genetic interaction network for Enhancers & Suppressors
      Phenotypic Class
      Suppressor of
      Statement
      Reference

      ftzhb.PP is a suppressor of lethal | female phenotype of hryhb.PP

      (Dawson et al., 1995)
      Phenotype Manifest In
      Additional Comments
      Genetic Interactions
      Statement
      Reference
      Xenogenetic Interactions
      Statement
      Reference
      Complementation and Rescue Data
      Partially rescues

      ftzhb.PP partially rescues ftzunspecified

      (Parkhurst and Ish-Horowicz, 1991)
      Comments

      ftzhb.PP partially rescues the pattern defects of mutant embryos deficient for ftz : the T1 'beard' is restored, as are various chitinised mouthpart structures.

      (Parkhurst and Ish-Horowicz, 1991)
      Images (0)
      Mutant
      Wild-type
      Stocks (0)
      Notes on Origin
      Discoverer
      External Crossreferences and Linkouts ( 0 )
      Synonyms and Secondary IDs (2)
      Reported As
      Symbol Synonym
      ftzhb.PP
      Name Synonyms
      hunchback promoter construct of Parkhurst
      (Parkhurst and Ish-Horowicz, 1991)
      Secondary FlyBase IDs
        References (2)