FB2024_03 , released June 25, 2024
Allele: Dmel\Acp26AaUAS.cPa
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General Information
Symbol
Dmel\Acp26AaUAS.cPa
Species
D. melanogaster
Name
Saccharomyces cerevisiae UAS construct a of Park
FlyBase ID
FBal0047987
Feature type
allele
Associated gene
Associated Insertion(s)
Carried in Construct
Key Links
Nature of the Allele
Progenitor genotype
Carried in construct
Cytology
Description

Expression of a full length Acp26Aa cDNA included within a 0.7kb EcoRI fragment is governed by UAS regulatory sequences.

Allele components
Component
Use(s)
Encoded product / tool
Mutations Mapped to the Genome
Curation Data
Type
Location
Additional Notes
References
Variant Molecular Consequences
Associated Sequence Data
DNA sequence
Protein sequence
 
Expression Data
Reporter Expression
Additional Information
Statement
Reference
 
Marker for
Reflects expression of
Reporter construct used in assay
Human Disease Associations
Disease Ontology (DO) Annotations
Models Based on Experimental Evidence ( 0 )
Disease
Evidence
References
Modifiers Based on Experimental Evidence ( 0 )
Disease
Interaction
References
Comments on Models/Modifiers Based on Experimental Evidence ( 0 )
 
Disease-implicated variant(s)
 
Phenotypic Data
Phenotypic Class
Phenotype Manifest In
Detailed Description
Statement
Reference

When Acp26AaScer\UAS.cPa is driven by Scer\GAL4hs.PB, in virgin females the release of oocytes fro the ovary is stimulated. The number of eggs in the reproductive tract is elevated. By 18h after heat shock, 67% of mutant females have an egg in the reproductive tract (as opposed to 8.3% in controls); most eggs are in the lateral oviducts. By 24h after heat shock, 17% of mutant females have more than one egg in their oviducts, and 12% had released eggs simultaneously into both lateral oviducts, a phenotype not seen in controls. No significant difference is found between the number of eggs in the reproductive tracts of mutant females at 18, 24, and 39h after heat shock. 18h after heat shock, 18% of mutant and control females deposit eggs. 24h heat shock however, 37% of mutant females desposit 4.2+-1.2 eggs per female. The number of eggs deposited by mutant females increases with time after heat shock, however, the average number of eggs deposited is very low compared to wild-type.

Expression of Acp26AaScer\UAS.cPa under the control of Scer\GAL4hs.PB, using heat shock, does not affect viability, when a single heat shock is applied during the L1 (day 1), L2 (day 2), L3 (day 3 or 4) or pupal stage (day 5, 6, 7 or 9).

External Data
Interactions
Show genetic interaction network for Enhancers & Suppressors
Phenotypic Class
Phenotype Manifest In
Additional Comments
Genetic Interactions
Statement
Reference
Xenogenetic Interactions
Statement
Reference
Complementation and Rescue Data
Comments
Images (0)
Mutant
Wild-type
Stocks (0)
Notes on Origin
Discoverer
External Crossreferences and Linkouts ( 0 )
Synonyms and Secondary IDs (3)
Reported As
Symbol Synonym
Acp26AaScer\UAS.cPa
Acp26AaUAS.cPa
Name Synonyms
Saccharomyces cerevisiae UAS construct a of Park
Secondary FlyBase IDs
    References (4)